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Mammalian Phenotype (MP): abnormal body weight

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   growth/size/body region phenotype [MP:0005378] <12>(64|95) (71|47|27)
+ + 2:   abnormal postnatal growth/weight/body size [MP:0002089] <3>(37|51) (41|31|14)
+ 1:   abnormal body size [MP:0003956] <5>(27|40) (30|19|7)
0:   abnormal body weight [MP:0001259] <4>(21|28) (24|14|7)
- 1:   abnormal susceptibility to weight gain [MP:0011117] <2>(3|3) (4|2|1)
- 1:   abnormal susceptibility to weight loss [MP:0011118] <2>(2|0) (2|0|0)
- 1:   decreased body weight [MP:0001262] <2>(6|11) (7|6|3)
- 1:   increased body weight [MP:0001260] <1>(7|7) (7|4|2)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
FtsH protease domain-like0Direct
Guanido kinase N-terminal domain0Direct
p53 tetramerization domain0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Assembly domain of cartilage oligomeric matrix protein0Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0001453Direct
Riboflavin synthase domain-like0.0001453Direct
Flavoproteins0.0008621Direct
KA1-like0.00266Inherited
Family A G protein-coupled receptor-like0.0118Inherited
GroEL equatorial domain-like0.06103Inherited
GroEL apical domain-like0.06103Inherited
4-helical cytokines0.07263Inherited
Acid proteases0.0874Inherited
Clathrin adaptor appendage domain0.2943Inherited
Hormone receptor domain0.3201Inherited
L domain-like0.3562Inherited
YWTD domain0.6527Inherited
STAT0.8377Inherited
Transcription factor STAT-4 N-domain0.8377Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
N-acetylmuramoyl-L-alanine amidase-like0Direct
Guanido kinase catalytic domain0Direct
Assembly domain of cartilage oligomeric matrix protein0Direct
Retinoblastoma tumor suppressor domains0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
p53 DNA-binding domain-like0Direct
PAS domain of steroid receptor coactivator 1A, NCo-A10Direct
FtsH protease domain-like0Direct
NADPH-cytochrome p450 reductase-like0Direct
Guanido kinase N-terminal domain0Direct
p53 tetramerization domain0Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0Direct
RUNT domain0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.0000003151Direct
Inositol polyphosphate 5-phosphatase (IPP5)0.0001825Direct
Phoshoinositide 3-kinase (PI3K) helical domain0.000594Direct
Pepsin-like0.005872Inherited
Rhodopsin-like0.007948Inherited
gamma-adaptin C-terminal appendage domain-like0.01746Inherited
Kinase associated domain 1, KA10.01746Inherited
VHS domain0.1481Inherited
DEP domain0.2084Inherited
Hormone receptor domain0.2771Inherited
YWTD domain0.6104Inherited
STAT DNA-binding domain0.8073Inherited
STAT0.8073Inherited
Transcription factor STAT-4 N-domain0.8073Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Guanido kinase N-terminal domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
p53 tetramerization domain0Direct
FtsH protease domain-like0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Assembly domain of cartilage oligomeric matrix protein0Direct
Riboflavin synthase domain-like0.00007238Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.00007238Direct
Flavoproteins0.000467Direct
FabD/lysophospholipase-like0.0007216Direct
KA1-like0.001531Inherited
Family A G protein-coupled receptor-like0.007468Inherited
ENTH/VHS domain0.01392Inherited
GroEL apical domain-like0.04401Inherited
GroEL equatorial domain-like0.04401Inherited
4-helical cytokines0.05332Inherited
Acid proteases0.06509Inherited
Clathrin adaptor appendage domain0.2514Inherited
Hormone receptor domain0.276Inherited
L domain-like0.3106Inherited
TNF-like0.6082Inherited
YWTD domain0.6094Inherited
STAT0.8057Inherited
Transcription factor STAT-4 N-domain0.8057Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52540,140990
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 140990 - FtsH protease domain-like
  • 0Direct
    54236,57889
  • 54236 - Ubiquitin-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    48034,55931
  • 48034 - Guanido kinase N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 0Direct
    57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.000467Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0007216Direct
    111418,81321
  • 111418 - Hormone receptor domain
  • 81321 - Family A G protein-coupled receptor-like
  • 0.02884Inherited
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.1912Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.7047Inherited
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.7388Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.8057Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.8057Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.8057Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57850,49599,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0Direct
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.000467Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.7047Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.8057Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.8057Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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