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Mammalian Phenotype (MP): abnormal hemoglobin

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   mammalian phenotype [MP:0000001] <29>
+ + + + + 5:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + 4:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(57|86) (66|47|21)
+ + + 3:   abnormal hematopoietic cell morphology [MP:0013656] <9>(48|77) (60|43|18)
+ + + 3:   abnormal myeloid cell morphology [MP:0013658] <8>(19|41) (26|23|8)
+ + 2:   abnormal erythroid lineage cell morphology [MP:0013659] <5>(8|14) (9|12|6)
+ + 2:   abnormal blood cell morphology [MP:0013657] <4>(31|49) (37|35|14)
+ 1:   abnormal erythrocyte morphology [MP:0002447] <30>(6|12) (7|10|4)
0:   abnormal hemoglobin [MP:0001588] <3>(2|7) (4|7|3)
- 1:   abnormal hemoglobin content [MP:0005563] <5>(0|2) (1|3|1)
- 1:   abnormal mean corpuscular hemoglobin [MP:0001589] <2>(2|4) (2|3|2)
- 1:   abnormal mean corpuscular hemoglobin concentration [MP:0005640] <2>(0|0) (1|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
STAT0.002194Inherited
Transcription factor STAT-4 N-domain0.002194Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Noncollagenous (NC1) domain of collagen IV0.00002481Direct
Short-chain cytokines0.0001919Direct
Eps15 homology domain (EH domain)0.0007276Direct
STAT DNA-binding domain0.001421Inherited
STAT0.001421Inherited
Transcription factor STAT-4 N-domain0.001421Inherited
Hypoxia-inducible factor Hif2a, C-terminal domain0.002594Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
STAT0.001251Inherited
Transcription factor STAT-4 N-domain0.001251Inherited
PH domain-like0.2138Inherited
BAR/IMD domain-like0.2225Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.0005422Direct
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.0006411Direct
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.0007521Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.001251Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.001251Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.001251Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.003366Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.001251Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.001251Inherited
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.00215Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)