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Mammalian Phenotype (MP): abnormal gametogenesis

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   reproductive system phenotype [MP:0005389] <2>(38|58) (47|18|6)
+ 1:   abnormal reproductive system morphology [MP:0002160] <12>(28|46) (37|15|6)
0:   abnormal gametogenesis [MP:0001929] <7>(15|19) (19|3|1)
- 1:   abnormal meiosis [MP:0001930] <11>(4|5) (5|1|0)
- 1:   abnormal spermatogenesis [MP:0001156] <10>(8|13) (11|3|0)
- 1:   abnormal germ cell morphology [MP:0002208] <5>(11|12) (13|2|1)
- 1:   abnormal sperm number [MP:0002673] <3>(2|3) (4|1|0)
- 1:   abnormal oogenesis [MP:0001931] <2>(5|4) (5|0|0)
- 1:   abnormal DNA methylation during gametogenesis [MP:0008878](1|0) (1|0|0)
- 1:   transmission ratio distortion [MP:0004179](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
SMAD MH1 domain0.000008102Direct
PAZ domain0.0002003Direct
The spindle assembly checkpoint protein mad20.0008931Direct
Nucleic acid-binding proteins0.006517Inherited
SMAD/FHA domain0.009179Inherited
Ribosomal protein S5 domain 2-like0.07008Inherited
SAICAR synthase-like0.07436Inherited
Tudor/PWWP/MBT0.1271Inherited
Cystine-knot cytokines0.1927Inherited
Bcl-2 inhibitors of programmed cell death0.2599Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.2906Inherited
BAR/IMD domain-like0.4102Inherited
Cysteine-rich DNA binding domain, (DM domain)0.4867Inherited
Nuclear receptor ligand-binding domain0.7137Inherited
Fibronectin type III0.9307Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
SMAD domain0.000004107Direct
SMAD MH1 domain0.000004107Direct
PAZ domain0.0001094Direct
DNA gyrase/MutL, second domain0.0005178Direct
The spindle assembly checkpoint protein mad20.0005178Direct
DNA gyrase/MutL, N-terminal domain0.0005178Direct
Single strand DNA-binding domain, SSB0.0007179Direct
Gonadodropin/Follitropin0.001836Inherited
Histone lysine methyltransferases0.0239Inherited
Tudor domain0.09387Inherited
Insulin-like0.1464Inherited
Bcl-2 inhibitors of programmed cell death0.2161Inherited
Transforming growth factor (TGF)-beta0.2268Inherited
Protein kinases, catalytic subunit0.3611Inherited
Cysteine-rich DNA binding domain, (DM domain)0.4335Inherited
PHD domain0.4624Inherited
Nuclear receptor ligand-binding domain0.6562Inherited
Fibronectin type III0.8988Inherited
I set domains0.9527Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SMAD MH1 domain0.000003526Direct
PAZ domain0.0001013Direct
The spindle assembly checkpoint protein mad20.0004842Direct
Nucleic acid-binding proteins0.003971Inherited
SMAD/FHA domain0.005693Inherited
dsRNA-binding domain-like0.03539Inherited
Ribosomal protein S5 domain 2-like0.05124Inherited
SAICAR synthase-like0.05465Inherited
Tudor/PWWP/MBT0.09865Inherited
"Winged helix" DNA-binding domain0.1245Inherited
Insulin-like0.1494Inherited
Cystine-knot cytokines0.1568Inherited
Bcl-2 inhibitors of programmed cell death0.2189Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.2479Inherited
BAR/IMD domain-like0.3635Inherited
Cysteine-rich DNA binding domain, (DM domain)0.439Inherited
Nuclear receptor ligand-binding domain0.6738Inherited
Fibronectin type III0.9067Inherited
Immunoglobulin1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.001728Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.001728Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.8564Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.4529Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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