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Mammalian Phenotype (MP): abnormal developmental patterning

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   embryo phenotype [MP:0005380] <7>(40|54) (46|28|19)
+ 1:   abnormal embryo development [MP:0001672] <5>(9|15) (11|11|5)
0:   abnormal developmental patterning [MP:0002084] <7>(7|12) (9|9|3)
- 1:   abnormal gastrulation [MP:0001695] <5>(4|7) (6|4|2)
- 1:   abnormal rostral-caudal axis patterning [MP:0005221] <5>(1|5) (1|1|0)
- 1:   abnormal left-right axis patterning [MP:0001706] <2>(0|1) (0|0|0)
- 1:   abnormal dorsal-ventral axis patterning [MP:0001704](0|0) (0|0|0)
- 1:   abnormal proximal-distal axis patterning [MP:0001705](0|0) (0|0|0)
- 1:   abnormal rostral-caudal body axis extension [MP:0003885](2|2) (3|2|0)
- 1:   mirror image duplication [MP:0009470](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Notch domain0.00001569Direct
Cullin repeat-like0.001663Inherited
Frizzled cysteine-rich domain0.03025Inherited
SMAD MH1 domain0.05182Inherited
WW domain0.06869Inherited
TIMP-like0.0851Inherited
SMAD/FHA domain0.1171Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Notch domain0.000008544Direct
Cullin repeat0.0001154Direct
C5 cytosine-specific DNA methylase, DCM0.0001154Direct
SCF ubiquitin ligase complex WHB domain0.0004394Direct
Linker histone H1/H50.005297Inherited
Frizzled cysteine-rich domain0.02358Inherited
Homeodomain0.0279Inherited
SMAD domain0.04124Inherited
SMAD MH1 domain0.04124Inherited
WW domain0.05441Inherited
Extracellular domain of cell surface receptors0.2734Inherited
DIX domain0.2734Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Notch domain0.000006974Direct
Cullin repeat-like0.0009366Direct
Cullin homology domain0.001817Inherited
Frizzled cysteine-rich domain0.02059Inherited
SMAD MH1 domain0.03667Inherited
WW domain0.05016Inherited
TIMP-like0.06319Inherited
SMAD/FHA domain0.09019Inherited
FnI-like domain0.4076Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.0001013Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0003906Direct
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.0003906Direct
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.0009366Direct
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.01628Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.0401Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.2566Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0001013Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0401Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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