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Mammalian Phenotype (MP): abnormal kidney morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   renal/urinary system phenotype [MP:0005367] <2>(41|47) (46|26|11)
+ 1:   abnormal renal/urinary system morphology [MP:0000516] <14>(31|36) (36|22|11)
0:   abnormal kidney morphology [MP:0002135] <29>(26|28) (28|15|6)
- 1:   abnormal kidney cortex morphology [MP:0000521] <9>(10|16) (12|9|3)
- 1:   abnormal kidney medulla morphology [MP:0003014] <9>(1|0) (1|0|0)
- 1:   abnormal nephron morphology [MP:0003881] <8>(19|22) (21|12|3)
- 1:   abnormal kidney blood vessel morphology [MP:0000530] <7>(5|5) (5|0|0)
- 1:   abnormal kidney pelvis morphology [MP:0004194] <7>(0|1) (0|0|0)
- 1:   abnormal kidney development [MP:0000527] <6>(2|3) (3|1|1)
- 1:   abnormal kidney collecting duct morphology [MP:0004754] <5>(0|0) (0|0|0)
- 1:   abnormal kidney size [MP:0002706] <5>(2|3) (2|5|2)
- 1:   kidney cysts [MP:0003675] <5>(1|0) (1|1|0)
- 1:   abnormal kidney epithelium morphology [MP:0004967] <3>(4|3) (4|2|0)
- 1:   abnormal kidney interstitium morphology [MP:0011425] <2>(0|0) (0|0|0)
- 1:   abnormal kidney iron level [MP:0008742] <2>(0|0) (0|0|0)
- 1:   renal fibrosis [MP:0003985] <2>(0|0) (2|0|0)
- 1:   ectopic kidney [MP:0003600] <1>(1|1) (1|0|0)
- 1:   kidney degeneration [MP:0009641] <1>(4|4) (4|0|0)
- 1:   abnormal kidney capsule morphology [MP:0011383](0|0) (0|0|0)
- 1:   abnormal kidney corticomedullary boundary morphology [MP:0011376](2|1) (2|1|1)
- 1:   abnormal kidney lobe morphology [MP:0011381](0|0) (0|0|0)
- 1:   abnormal kidney lobule morphology [MP:0011382](0|0) (0|0|0)
- 1:   absent kidney [MP:0000520](1|1) (2|0|0)
- 1:   bifid kidney [MP:0003601](0|0) (0|0|0)
- 1:   duplex kidney [MP:0004017](0|0) (0|1|1)
- 1:   fused kidneys [MP:0003605](0|0) (0|0|0)
- 1:   granular kidney [MP:0011534](0|0) (0|0|0)
- 1:   nephrocalcinosis [MP:0003197](0|0) (0|0|0)
- 1:   nephrolithiasis [MP:0002708](0|0) (0|0|0)
- 1:   nephrosclerosis [MP:0009860](0|0) (0|0|0)
- 1:   pale kidney [MP:0004969](0|1) (0|1|0)
- 1:   single kidney [MP:0003604](1|1) (1|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Families 57/38 glycoside transferase middle domain0.0002045Direct
(Trans)glycosidases0.0003083Direct
Glycoside hydrolase/deacetylase0.000831Direct
Galactose mutarotase-like0.002075Inherited
Flavoproteins0.002075Inherited
FnI-like domain0.003823Inherited
TNF receptor-like0.01426Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.01684Inherited
Riboflavin synthase domain-like0.01684Inherited
HCP-like0.01727Inherited
L30e-like0.02691Inherited
C-type lectin-like0.03409Inherited
Bcl-2 inhibitors of programmed cell death0.03862Inherited
Cadherin-like0.1842Inherited
Metalloproteases ("zincins"), catalytic domain0.2207Inherited
Cystine-knot cytokines0.3978Inherited
Sema domain0.7091Inherited
Integrin domains0.7472Inherited
CalX-like0.8302Inherited
Notch domain0.8302Inherited
Plexin repeat0.9002Inherited
Nuclear receptor ligand-binding domain0.9002Inherited
Homeodomain-like0.9061Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.9471Inherited
TPR-like0.9721Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
alpha-mannosidase, domain 20.0001277Direct
alpha-mannosidase0.0001277Direct
NADPH-cytochrome p450 reductase-like0.0001277Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.0001277Direct
Noncollagenous (NC1) domain of collagen IV0.000544Direct
VWC domain0.0008478Direct
alpha-mannosidase, C-terminal domain0.0009114Direct
Platelet-derived growth factor-like0.002963Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.005319Inherited
Laminin-type module0.006341Inherited
TNF receptor-like0.01443Inherited
Forkhead DNA-binding domain0.02643Inherited
Bcl-2 inhibitors of programmed cell death0.03014Inherited
Short-chain cytokines0.08634Inherited
Cadherin0.1419Inherited
Transforming growth factor (TGF)-beta0.5044Inherited
Homeodomain0.6176Inherited
Sema domain0.6729Inherited
Leucine zipper domain0.7129Inherited
Integrin domains0.7129Inherited
Notch domain0.8016Inherited
CalX-beta domain0.8016Inherited
Plexin repeat0.878Inherited
Nuclear receptor ligand-binding domain0.878Inherited
Nuclear receptor0.878Inherited
Tetratricopeptide repeat (TPR)0.9873Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Families 57/38 glycoside transferase middle domain0.0001035Direct
(Trans)glycosidases0.0001588Direct
Glycoside hydrolase/deacetylase0.0004492Direct
Flavoproteins0.001182Inherited
Galactose mutarotase-like0.001182Inherited
FnI-like domain0.002245Inherited
TNF receptor-like0.009144Inherited
Riboflavin synthase domain-like0.01092Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.01092Inherited
HCP-like0.01123Inherited
L30e-like0.01809Inherited
C-type lectin-like0.0234Inherited
Bcl-2 inhibitors of programmed cell death0.02672Inherited
Cadherin-like0.1491Inherited
Metalloproteases ("zincins"), catalytic domain0.1824Inherited
EGF/Laminin0.3342Inherited
Cystine-knot cytokines0.3512Inherited
Sema domain0.6688Inherited
Leucine zipper domain0.7089Inherited
Integrin domains0.7089Inherited
CalX-like0.7976Inherited
Notch domain0.7976Inherited
Plexin repeat0.8733Inherited
Nuclear receptor ligand-binding domain0.8733Inherited
Homeodomain-like0.8797Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.9252Inherited
TPR-like0.9534Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
88713,88688
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 0.0001035Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.000775Direct
    48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.000775Direct
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.001182Inherited
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.006166Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.01904Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.04476Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.06272Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.2116Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.5956Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.6688Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.6688Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.6688Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.8959Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.9173Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0001123Direct
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.0004492Direct
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01809Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.1872Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.1902Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.7089Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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