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Mammalian Phenotype (MP): abnormal cochlear hair cell morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   mammalian phenotype [MP:0000001] <29>
+ + + + + + 6:   nervous system phenotype [MP:0003631] <2>(98|128) (113|79|50)
+ + + + + 5:   abnormal nervous system morphology [MP:0003632] <17>(76|104) (91|64|47)
+ + + + 4:   abnormal somatic nervous system morphology [MP:0002752] <7>(34|47) (37|25|14)
+ + + + 4:   abnormal membranous labyrinth morphology [MP:0000035] <2>(11|14) (12|9|5)
+ + + + 4:   hearing/vestibular/ear phenotype [MP:0005377] <2>(20|24) (23|14|5)
+ + + 3:   abnormal ear morphology [MP:0002102] <4>(16|21) (18|14|5)
+ + + 3:   abnormal cochlear labyrinth morphology [MP:0004426] <1>(10|12) (11|8|5)
+ + + 3:   abnormal somatic sensory system morphology [MP:0000959] <4>(26|38) (29|19|12)
+ + 2:   abnormal cochlea morphology [MP:0000031] <15>(12|14) (13|8|5)
+ + 2:   abnormal scala media morphology [MP:0003169] <9>(10|12) (11|8|5)
+ + 2:   abnormal inner ear morphology [MP:0000026] <15>(13|15) (13|11|5)
+ + 2:   abnormal mechanoreceptor morphology [MP:0000972] <4>(10|12) (10|7|5)
+ 1:   abnormal cochlear sensory epithelium morphology [MP:0003308] <1>(10|12) (10|7|5)
+ 1:   abnormal organ of Corti morphology [MP:0000042] <7>(10|12) (10|7|5)
+ 1:   abnormal hair cell morphology [MP:0000045] <3>(10|12) (10|7|5)
0:   abnormal cochlear hair cell morphology [MP:0002622] <6>(10|12) (10|7|5)
- 1:   abnormal cochlear hair cell stereociliary bundle morphology [MP:0004521] <8>(5|7) (6|2|1)
- 1:   abnormal cochlear inner hair cell morphology [MP:0004393] <6>(5|5) (5|4|4)
- 1:   abnormal cochlear outer hair cell morphology [MP:0004399] <6>(5|10) (6|7|5)
- 1:   abnormal cochlear hair cell number [MP:0004406] <2>(1|3) (1|3|4)
- 1:   cochlear hair cell degeneration [MP:0004362] <2>(1|1) (1|1|0)
- 1:   abnormal cochlear hair cell development [MP:0004589](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Frizzled cysteine-rich domain0.00004749Direct
Nicotinic receptor ligand binding domain-like0.001271Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.001271Inherited
Cadherin-like0.001833Inherited
Growth factor receptor domain0.002437Inherited
EGF/Laminin0.006674Inherited
lambda repressor-like DNA-binding domains0.01117Inherited
PDZ domain-like0.01118Inherited
Second domain of FERM0.03103Inherited
SH3-domain0.3783Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Frizzled cysteine-rich domain0.00002434Direct
DIX domain0.00003936Direct
DEP domain0.0005208Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0007405Direct
Nicotinic receptor ligand binding domain-like0.0007405Direct
Growth factor receptor domain0.0007594Direct
Cadherin0.0008453Direct
PDZ domain0.001075Inherited
POU-specific domain0.002434Inherited
EGF-type module0.01974Inherited
Motor proteins0.01976Inherited
SH3-domain0.3369Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Frizzled cysteine-rich domain0.0000223Direct
Nicotinic receptor ligand binding domain-like0.0007055Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0007055Direct
Cadherin-like0.001037Inherited
Growth factor receptor domain0.001398Inherited
EGF/Laminin0.004072Inherited
lambda repressor-like DNA-binding domains0.007039Inherited
PDZ domain-like0.007049Inherited
Second domain of FERM0.02118Inherited
SH3-domain0.3322Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0003285Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.0007055Direct
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0007055Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.001961Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.003175Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.003956Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.007039Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0002837Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0004912Direct
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0005338Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0009073Direct
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0009073Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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