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Mammalian Phenotype (MP): abnormal scala media morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   hearing/vestibular/ear phenotype [MP:0005377] <2>(20|24) (23|14|5)
+ + + 3:   abnormal ear morphology [MP:0002102] <4>(16|21) (18|14|5)
+ + 2:   abnormal membranous labyrinth morphology [MP:0000035] <2>(11|14) (12|9|5)
+ + 2:   abnormal inner ear morphology [MP:0000026] <15>(13|15) (13|11|5)
+ 1:   abnormal cochlear labyrinth morphology [MP:0004426] <1>(10|12) (11|8|5)
+ 1:   abnormal cochlea morphology [MP:0000031] <15>(12|14) (13|8|5)
0:   abnormal scala media morphology [MP:0003169] <9>(10|12) (11|8|5)
- 1:   abnormal organ of Corti morphology [MP:0000042] <7>(10|12) (10|7|5)
- 1:   abnormal stria vascularis morphology [MP:0000048] <6>(1|1) (1|1|0)
- 1:   abnormal tectorial membrane morphology [MP:0003149] <6>(0|0) (0|0|0)
- 1:   abnormal spiral ligament morphology [MP:0004288] <3>(2|2) (2|1|0)
- 1:   abnormal Hensen stripe morphology [MP:0013961] <1>(0|0) (0|0|0)
- 1:   small scala media [MP:0008308] <1>(0|0) (1|0|0)
- 1:   abnormal Claudius cell morphology [MP:0004430](0|0) (0|0|0)
- 1:   absent scala media [MP:0000033](0|0) (0|0|0)
- 1:   dilated scala media [MP:0008309](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Frizzled cysteine-rich domain0.0001098Direct
Growth factor receptor domain0.001909Inherited
EGF/Laminin0.002354Inherited
Nicotinic receptor ligand binding domain-like0.002634Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.002634Inherited
Cadherin-like0.003758Inherited
lambda repressor-like DNA-binding domains0.0175Inherited
PDZ domain-like0.02394Inherited
Second domain of FERM0.04709Inherited
SH3-domain0.4961Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Frizzled cysteine-rich domain0.0000556Direct
DIX domain0.00006921Direct
DEP domain0.0008744Direct
Neurotransmitter-gated ion-channel transmembrane pore0.001539Inherited
Nicotinic receptor ligand binding domain-like0.001539Inherited
Growth factor receptor domain0.001738Inherited
Cadherin0.001751Inherited
PDZ domain0.002639Inherited
POU-specific domain0.004016Inherited
EGF-type module0.0116Inherited
Motor proteins0.0326Inherited
SH3-domain0.4476Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Frizzled cysteine-rich domain0.00005346Direct
Growth factor receptor domain0.001083Inherited
EGF/Laminin0.001347Inherited
Nicotinic receptor ligand binding domain-like0.001515Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.001515Inherited
Cadherin-like0.002204Inherited
lambda repressor-like DNA-binding domains0.01141Inherited
PDZ domain-like0.01594Inherited
Second domain of FERM0.03316Inherited
SH3-domain0.4484Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.6415Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0006448Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.0007407Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.001515Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.001515Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001772Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.003691Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.006568Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.01141Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0006283Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0008534Direct
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.001157Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.001558Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001558Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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