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Mammalian Phenotype (MP): abnormal retinal layer morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   mammalian phenotype [MP:0000001] <29>
+ + + + + 5:   vision/eye phenotype [MP:0005391] <2>(43|53) (50|27|17)
+ + + + 4:   abnormal eye morphology [MP:0002092] <23>(39|49) (46|25|15)
+ + + 3:   abnormal posterior eye segment morphology [MP:0005195] <4>(21|24) (23|14|8)
+ + 2:   abnormal ocular fundus morphology [MP:0002864] <2>(19|23) (21|14|8)
+ 1:   abnormal retina morphology [MP:0001325] <23>(19|23) (21|14|8)
0:   abnormal retinal layer morphology [MP:0003727] <3>(11|16) (12|8|6)
- 1:   abnormal retinal neuronal layer morphology [MP:0006069] <7>(11|15) (11|8|5)
- 1:   abnormal retinal pigment epithelium morphology [MP:0005201] <3>(0|1) (1|0|1)
- 1:   disorganized retinal layers [MP:0001328](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
GAF domain-like0.001316Inherited
E2F-DP heterodimerization region0.002473Inherited
Clc chloride channel0.004107Inherited
HD-domain/PDEase-like0.05597Inherited
TNF-like0.179Inherited
Sema domain0.1899Inherited
HLH, helix-loop-helix DNA-binding domain0.3101Inherited
Tetraspanin0.32Inherited
CBS-domain pair0.32Inherited
Plexin repeat0.6193Inherited
Cyclin-like0.656Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
E2F dimerization segment0.0008724Direct
GAF domain0.0008724Direct
Clc chloride channel0.002887Inherited
Cell cycle transcription factor e2f-dp0.004485Inherited
Extracellular domain of cell surface receptors0.006492Inherited
cAMP-binding domain0.03242Inherited
POU-specific domain0.03341Inherited
PDEase0.03341Inherited
TNF-like0.1469Inherited
Sema domain0.1567Inherited
HLH, helix-loop-helix DNA-binding domain0.2693Inherited
CBS-domain pair0.28Inherited
Calmodulin-like0.28Inherited
YWTD domain0.28Inherited
Plexin repeat0.5771Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
GAF domain-like0.0007308Direct
E2F-DP heterodimerization region0.001421Inherited
Clc chloride channel0.002426Inherited
HD-domain/PDEase-like0.03998Inherited
TNF-like0.1442Inherited
Sema domain0.1541Inherited
HLH, helix-loop-helix DNA-binding domain0.2663Inherited
Tetraspanin0.276Inherited
CBS-domain pair0.276Inherited
YWTD domain0.276Inherited
Plexin repeat0.5741Inherited
Cyclin-like0.6128Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.0007308Direct
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.0007308Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.001421Inherited
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0.001421Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.04604Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.1541Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.33Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.9863Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.00007712Direct
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.0007308Direct
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.002426Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.1998Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.276Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.6483Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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