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Mammalian Phenotype (MP): decreased B cell number

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + + + 9:   mammalian phenotype [MP:0000001] <29>
+ + + + + + + 7:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + + + 6:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + + + 6:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(57|86) (66|47|21)
+ + + + + 5:   abnormal immune system morphology [MP:0000685] <3>(50|76) (60|35|18)
+ + + + + 5:   abnormal hematopoietic cell morphology [MP:0013656] <9>(48|77) (60|43|18)
+ + + + 4:   abnormal leukocyte morphology [MP:0008246] <4>(36|62) (47|29|15)
+ + + + 4:   abnormal mononuclear cell morphology [MP:0008247] <2>(33|57) (41|28|14)
+ + + + 4:   abnormal hematopoietic cell number [MP:0011180] <7>(34|57) (43|29|13)
+ + + + 4:   abnormal immune system cell morphology [MP:0000716] <5>(37|63) (48|29|16)
+ + + 3:   abnormal lymphocyte morphology [MP:0002619] <5>(27|46) (33|26|14)
+ + + 3:   decreased hematopoietic cell number [MP:0011182] <5>(21|34) (27|21|11)
+ + + 3:   abnormal leukocyte cell number [MP:0000217] <8>(29|49) (37|25|12)
+ + + 3:   abnormal professional antigen presenting cell morphology [MP:0008195] <3>(16|32) (20|11|5)
+ + 2:   abnormal mature B cell morphology [MP:0008171] <9>(8|21) (10|8|4)
+ + 2:   abnormal B cell morphology [MP:0004939] <6>(17|28) (20|11|6)
+ + 2:   decreased leukocyte cell number [MP:0000221] <5>(17|28) (24|18|10)
+ + 2:   abnormal lymphocyte cell number [MP:0000717] <6>(18|38) (25|21|9)
+ 1:   abnormal B cell number [MP:0002458] <6>(7|18) (8|8|4)
+ 1:   decreased lymphocyte cell number [MP:0005016] <5>(16|28) (22|16|7)
0:   decreased B cell number [MP:0005017] <4>(6|11) (7|6|4)
- 1:   decreased mature B cell number [MP:0008211] <9>(3|7) (4|3|1)
- 1:   absent B cells [MP:0008071] <2>(0|1) (0|0|0)
- 1:   decreased immature B cell number [MP:0008215] <2>(3|4) (3|5|1)
- 1:   decreased pre-B cell number [MP:0008209] <1>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Ran binding protein zinc finger-like0.00002645Direct
WWE domain0.003654Inherited
SH2 domain0.02816Inherited
Calponin-homology domain, CH-domain0.04407Inherited
Bcl-2 inhibitors of programmed cell death0.07199Inherited
DBL homology domain (DH-domain)0.2207Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Ran binding protein zinc finger-like0.00001739Direct
WWE domain0.001328Inherited
Interferon regulatory factor 3 (IRF3), transactivation domain0.002543Inherited
SH2 domain0.02045Inherited
Calponin-homology domain, CH-domain0.03688Inherited
Bcl-2 inhibitors of programmed cell death0.05508Inherited
Interferon regulatory factor0.05508Inherited
Toll/Interleukin receptor TIR domain0.08876Inherited
Pleckstrin-homology domain (PH domain)0.1364Inherited
DBL homology domain (DH-domain)0.188Inherited
PLC-like (P variant)0.1999Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Ran binding protein zinc finger-like0.00001209Direct
WWE domain0.002143Inherited
SH2 domain0.01903Inherited
Calponin-homology domain, CH-domain0.0308Inherited
Bcl-2 inhibitors of programmed cell death0.0528Inherited
Toll/Interleukin receptor TIR domain0.1655Inherited
DBL homology domain (DH-domain)0.1824Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.00004331Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.0528Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.06343Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.1824Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.2242Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    50729,50044,55550
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0Direct
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0001215Direct
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0001215Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)