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Mammalian Phenotype (MP): digestive/alimentary phenotype

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   mammalian phenotype [MP:0000001] <29>
0:   digestive/alimentary phenotype [MP:0005381] <2>(38|46) (40|19|9)
- 1:   abnormal digestive system morphology [MP:0000462] <21>(30|38) (31|13|3)
- 1:   abnormal digestive system physiology [MP:0001663] <18>(16|16) (17|7|5)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Hedgehog/intein (Hint) domain0Direct
p53 tetramerization domain0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Hedgehog/DD-peptidase0Direct
p53-like transcription factors0.00000001257Direct
Homeodomain-like0.000003004Direct
Cystine-knot cytokines0.000006228Direct
SMAD MH1 domain0.0003057Direct
Nuclear receptor ligand-binding domain0.0004926Direct
SpoIIaa-like0.003366Inherited
HMG-box0.003932Inherited
FnI-like domain0.005796Inherited
Kringle-like0.007084Inherited
4-helical cytokines0.008143Inherited
"Winged helix" DNA-binding domain0.009672Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.01123Inherited
Integrin beta tail domain0.01142Inherited
DEATH domain0.01672Inherited
Notch domain0.01757Inherited
DNA repair protein MutS, domain III0.01757Inherited
Growth factor receptor domain0.01923Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.01999Inherited
Riboflavin synthase domain-like0.01999Inherited
HLH, helix-loop-helix DNA-binding domain0.03246Inherited
Trefoil0.03537Inherited
Flavoproteins0.05837Inherited
Toll/Interleukin receptor TIR domain0.06782Inherited
Calponin-homology domain, CH-domain0.08568Inherited
SEA domain0.08588Inherited
Intermediate filament protein, coiled coil region0.09486Inherited
SMAD/FHA domain0.2627Inherited
Family A G protein-coupled receptor-like0.2971Inherited
MFS general substrate transporter0.3088Inherited
Rhodanese/Cell cycle control phosphatase0.4153Inherited
RNI-like0.4831Inherited
DBL homology domain (DH-domain)0.8195Inherited
RING/U-box0.9691Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Hedgehog (development protein), N-terminal signaling domain0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
p53 DNA-binding domain-like0Direct
Hedgehog C-terminal (Hog) autoprocessing domain0Direct
p53 tetramerization domain0Direct
Forkhead DNA-binding domain0.00000002751Direct
Homeodomain0.000001211Direct
Rel/Dorsal transcription factors, DNA-binding domain0.00001087Direct
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.00008298Direct
Transforming growth factor (TGF)-beta0.0002073Direct
SMAD domain0.0002288Direct
SMAD MH1 domain0.0002288Direct
Nuclear receptor ligand-binding domain0.0005154Direct
Nuclear receptor0.000858Direct
Interleukin 17F, IL-17F0.0009959Direct
EGF-type module0.001889Inherited
T-box0.003368Inherited
Kringle modules0.003574Inherited
HMG-box0.003901Inherited
Cytochrome p450 reductase N-terminal domain-like0.004476Inherited
Pyrin domain, PYD0.009196Inherited
Integrin beta tail domain0.009196Inherited
VWC domain0.009974Inherited
Notch domain0.01408Inherited
DNA repair protein MutS, domain III0.01408Inherited
NADPH-cytochrome p450 reductase-like0.01408Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.01408Inherited
Paired domain0.02894Inherited
Interferons/interleukin-10 (IL-10)0.02894Inherited
Pyridoxal-dependent decarboxylase0.02914Inherited
Trefoil0.02914Inherited
Short-chain cytokines0.03674Inherited
HLH, helix-loop-helix DNA-binding domain0.03754Inherited
Ephrin ectodomain0.04986Inherited
Caspase recruitment domain, CARD0.08381Inherited
Calponin-homology domain, CH-domain0.08589Inherited
Intermediate filament protein, coiled coil region0.09439Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.107Inherited
Toll/Interleukin receptor TIR domain0.1168Inherited
ABC transporter ATPase domain-like0.1633Inherited
Cell cycle control phosphatase, catalytic domain0.1721Inherited
28-residue LRR0.1913Inherited
Papain-like0.2475Inherited
Classic zinc finger, C2H20.7105Inherited
DBL homology domain (DH-domain)0.8291Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
p53 tetramerization domain0Direct
Hedgehog/intein (Hint) domain0Direct
Hedgehog/DD-peptidase0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
p53-like transcription factors0.000000004778Direct
Homeodomain-like0.000001268Direct
Cystine-knot cytokines0.000002683Direct
SMAD MH1 domain0.0001574Direct
Nuclear receptor ligand-binding domain0.0002596Direct
EGF/Laminin0.001926Inherited
SpoIIaa-like0.001964Inherited
HMG-box0.002315Inherited
FnI-like domain0.003495Inherited
Kringle-like0.004337Inherited
4-helical cytokines0.005019Inherited
"Winged helix" DNA-binding domain0.006027Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.007085Inherited
Integrin beta tail domain0.007211Inherited
DEATH domain0.01083Inherited
Notch domain0.01144Inherited
DNA repair protein MutS, domain III0.01144Inherited
Growth factor receptor domain0.01257Inherited
Riboflavin synthase domain-like0.0131Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0131Inherited
HLH, helix-loop-helix DNA-binding domain0.0222Inherited
Trefoil0.02433Inherited
Flavoproteins0.04187Inherited
Toll/Interleukin receptor TIR domain0.04944Inherited
Calponin-homology domain, CH-domain0.06366Inherited
SEA domain0.06383Inherited
Intermediate filament protein, coiled coil region0.07117Inherited
SMAD/FHA domain0.2215Inherited
Family A G protein-coupled receptor-like0.2539Inherited
MFS general substrate transporter0.265Inherited
Rhodanese/Cell cycle control phosphatase0.3682Inherited
RNI-like0.4354Inherited
Cytochrome P4500.4921Inherited
DBL homology domain (DH-domain)0.786Inherited
RING/U-box0.95Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55166,51294
  • 55166 - Hedgehog/DD-peptidase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.000006319Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.0001574Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.0005017Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.0006214Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0007199Direct
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001964Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.001964Inherited
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.007211Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.009473Inherited
    55550,50729
  • 55550 - SH2 domain
  • 50729 - PH domain-like
  • 0.01144Inherited
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01144Inherited
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.02029Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.03987Inherited
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.04187Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.08997Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.7516Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.0007563Direct
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0007563Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.003578Inherited
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.007211Inherited
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.01144Inherited
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.04187Inherited
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.04187Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.04892Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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