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Mammalian Phenotype (MP): abnormal retinal neuronal layer morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   mammalian phenotype [MP:0000001] <29>
+ + + + + + 6:   vision/eye phenotype [MP:0005391] <2>(43|53) (50|27|17)
+ + + + + 5:   abnormal eye morphology [MP:0002092] <23>(39|49) (46|25|15)
+ + + + 4:   abnormal posterior eye segment morphology [MP:0005195] <4>(21|24) (23|14|8)
+ + + 3:   abnormal ocular fundus morphology [MP:0002864] <2>(19|23) (21|14|8)
+ + 2:   abnormal retina morphology [MP:0001325] <23>(19|23) (21|14|8)
+ 1:   abnormal retinal layer morphology [MP:0003727] <3>(11|16) (12|8|6)
0:   abnormal retinal neuronal layer morphology [MP:0006069] <7>(11|15) (11|8|5)
- 1:   abnormal retinal ganglion layer morphology [MP:0005241] <5>(2|5) (3|2|1)
- 1:   abnormal retinal outer nuclear layer morphology [MP:0003731] <3>(2|1) (2|0|0)
- 1:   abnormal retinal inner nuclear layer morphology [MP:0003733] <2>(2|2) (2|0|0)
- 1:   abnormal retinal inner plexiform layer morphology [MP:0003734] <2>(2|2) (2|1|0)
- 1:   abnormal retinal outer plexiform layer morphology [MP:0003732] <2>(0|0) (0|0|0)
- 1:   abnormal retinal photoreceptor layer morphology [MP:0003728] <1>(4|7) (5|3|2)
- 1:   abnormal retinal nerve fiber layer morphology [MP:0006303](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Sema domain0.0000235Direct
Plexin repeat0.0001738Direct
GAF domain-like0.0006411Direct
E2F-DP heterodimerization region0.001224Inherited
Clc chloride channel0.002051Inherited
CBS-domain pair0.01077Inherited
Tetraspanin0.01651Inherited
TNF-like0.01738Inherited
Cyclin-like0.02001Inherited
HD-domain/PDEase-like0.03182Inherited
HLH, helix-loop-helix DNA-binding domain0.6396Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
Sema domain0.00001606Direct
Plexin repeat0.0001231Direct
E2F dimerization segment0.0004155Direct
GAF domain0.0004155Direct
Clc chloride channel0.00141Inherited
Cell cycle transcription factor e2f-dp0.002209Inherited
Extracellular domain of cell surface receptors0.003265Inherited
CBS-domain pair0.006132Inherited
TNF-like0.01376Inherited
POU-specific domain0.01826Inherited
PDEase0.01826Inherited
Calmodulin-like0.07031Inherited
cAMP-binding domain0.5304Inherited
HLH, helix-loop-helix DNA-binding domain0.6067Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Sema domain0.00001068Direct
Plexin repeat0.0000872Direct
GAF domain-like0.0003423Direct
E2F-DP heterodimerization region0.0006757Direct
Clc chloride channel0.001167Inherited
CBS-domain pair0.006761Inherited
Tetraspanin0.01068Inherited
TNF-like0.01131Inherited
Cyclin-like0.01312Inherited
HD-domain/PDEase-like0.02175Inherited
HLH, helix-loop-helix DNA-binding domain0.5954Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.00001068Direct
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.0003423Direct
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.0003423Direct
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.0004202Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.0006757Direct
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0.0006757Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.02006Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.02521Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.00003403Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0001577Direct
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.0003423Direct
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.0007782Direct
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001167Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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