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Mammalian Phenotype (MP): abnormal inner ear morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   hearing/vestibular/ear phenotype [MP:0005377] <2>(20|24) (23|14|5)
+ 1:   abnormal ear morphology [MP:0002102] <4>(16|21) (18|14|5)
0:   abnormal inner ear morphology [MP:0000026] <15>(13|15) (13|11|5)
- 1:   abnormal cochlea morphology [MP:0000031] <15>(12|14) (13|8|5)
- 1:   abnormal inner ear vestibule morphology [MP:0000034] <4>(0|0) (0|0|0)
- 1:   abnormal hair cell morphology [MP:0000045] <3>(10|12) (10|7|5)
- 1:   abnormal inner ear canal morphology [MP:0002729] <3>(1|1) (1|2|0)
- 1:   abnormal membranous labyrinth morphology [MP:0000035] <2>(11|14) (12|9|5)
- 1:   abnormal otic capsule morphology [MP:0000039] <2>(0|1) (1|0|0)
- 1:   abnormal bony labyrinth [MP:0004289] <1>(0|0) (0|0|0)
- 1:   abnormal inner ear development [MP:0011238] <1>(1|0) (1|0|0)
- 1:   abnormal internal auditory canal morphology [MP:0004286](0|0) (0|0|0)
- 1:   abnormal pars superior vestibularis morphology [MP:0000028](0|0) (0|0|0)
- 1:   abnormal sulcus ampullaris morphology [MP:0000046](0|0) (0|0|0)
- 1:   abnormal vestibular aqueduct morphology [MP:0009821](0|0) (0|0|0)
- 1:   absent inner ear [MP:0006285](0|0) (0|0|0)
- 1:   inner ear cysts [MP:0006287](0|0) (0|0|0)
- 1:   inner ear hypoplasia [MP:0006286](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Cytokine0.001987Inherited
Cadherin-like0.002214Inherited
PDZ domain-like0.0743Inherited
EGF/Laminin0.1172Inherited
Frizzled cysteine-rich domain0.1456Inherited
Growth factor receptor domain0.2244Inherited
Second domain of FERM0.2791Inherited
lambda repressor-like DNA-binding domains0.2791Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.3191Inherited
Nicotinic receptor ligand binding domain-like0.3191Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.5095Inherited
Homeodomain-like0.6814Inherited
SH3-domain0.8581Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
DIX domain0.0001701Direct
Fibroblast growth factors (FGF)0.0004468Direct
Cadherin0.001057Inherited
DEP domain0.002007Inherited
EGF-type module0.01229Inherited
PDZ domain0.0542Inherited
Frizzled cysteine-rich domain0.1146Inherited
POU-specific domain0.2369Inherited
Nicotinic receptor ligand binding domain-like0.2729Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.2729Inherited
Growth factor receptor domain0.3573Inherited
Motor proteins0.3594Inherited
Paired domain0.4668Inherited
Homeodomain0.6932Inherited
SH3-domain0.8249Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Cytokine0.001129Inherited
Cadherin-like0.001263Inherited
PDZ domain-like0.05459Inherited
EGF/Laminin0.09026Inherited
Frizzled cysteine-rich domain0.1148Inherited
Growth factor receptor domain0.186Inherited
Second domain of FERM0.2371Inherited
lambda repressor-like DNA-binding domains0.2371Inherited
Nicotinic receptor ligand binding domain-like0.275Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.275Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.462Inherited
Homeodomain-like0.6395Inherited
SH3-domain0.8276Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0001799Direct
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.0004287Direct
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0008183Direct
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.003037Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.008729Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.1653Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.1653Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1752Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.2371Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.275Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.6485Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0001304Direct
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0005916Direct
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.003326Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.003326Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.2074Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)