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Mammalian Phenotype (MP): abnormal cochlea morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   hearing/vestibular/ear phenotype [MP:0005377] <2>(20|24) (23|14|5)
+ + 2:   abnormal ear morphology [MP:0002102] <4>(16|21) (18|14|5)
+ 1:   abnormal inner ear morphology [MP:0000026] <15>(13|15) (13|11|5)
0:   abnormal cochlea morphology [MP:0000031] <15>(12|14) (13|8|5)
- 1:   abnormal scala media morphology [MP:0003169] <9>(10|12) (11|8|5)
- 1:   abnormal Reissner membrane morphology [MP:0006021] <4>(0|0) (0|0|0)
- 1:   cochlear degeneration [MP:0000032] <3>(0|0) (1|0|0)
- 1:   abnormal Rosenthal canal morphology [MP:0004305] <2>(0|0) (0|0|0)
- 1:   abnormal modiolus morphology [MP:0003309] <2>(0|0) (0|0|0)
- 1:   abnormal spiral limbus morphology [MP:0004287] <2>(0|0) (0|0|0)
- 1:   abnormal cochlear sensory epithelium morphology [MP:0003308] <1>(10|12) (10|7|5)
- 1:   abnormal scala tympani morphology [MP:0003167] <1>(0|0) (0|0|0)
- 1:   abnormal Boettcher cell morphology [MP:0011739](0|0) (0|0|0)
- 1:   abnormal basilar membrane morphology [MP:0004308](0|0) (0|0|0)
- 1:   abnormal cochlear basement membrane morphology [MP:0004598](0|0) (0|0|0)
- 1:   abnormal scala vestibuli morphology [MP:0003168](0|0) (0|0|0)
- 1:   absent cochlea [MP:0003147](0|0) (0|0|0)
- 1:   decreased cochlear coiling [MP:0003148](1|0) (1|0|0)
- 1:   dilated cochlea [MP:0004493](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Frizzled cysteine-rich domain0.0001533Direct
Cytokine0.0009463Direct
Neurotransmitter-gated ion-channel transmembrane pore0.003545Inherited
Nicotinic receptor ligand binding domain-like0.003545Inherited
lambda repressor-like DNA-binding domains0.02108Inherited
PDZ domain-like0.03217Inherited
Second domain of FERM0.05569Inherited
Cadherin-like0.5286Inherited
SH3-domain0.5904Inherited
Growth factor receptor domain0.6244Inherited
EGF/Laminin0.7484Inherited
Homeodomain-like0.9743Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Frizzled cysteine-rich domain0.00008356Direct
DIX domain0.00009164Direct
Fibroblast growth factors (FGF)0.0001889Direct
Paired domain0.0005306Direct
DEP domain0.001136Inherited
Nicotinic receptor ligand binding domain-like0.002202Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.002202Inherited
Growth factor receptor domain0.002594Inherited
PDZ domain0.004076Inherited
POU-specific domain0.005092Inherited
Motor proteins0.04177Inherited
EGF-type module0.4148Inherited
Cadherin0.4709Inherited
SH3-domain0.5344Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Frizzled cysteine-rich domain0.00007652Direct
Cytokine0.0005142Direct
Nicotinic receptor ligand binding domain-like0.002077Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.002077Inherited
lambda repressor-like DNA-binding domains0.01388Inherited
PDZ domain-like0.022Inherited
Second domain of FERM0.03973Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.2945Inherited
Cadherin-like0.4814Inherited
SH3-domain0.5443Inherited
Growth factor receptor domain0.5796Inherited
EGF/Laminin0.7101Inherited
Homeodomain-like0.9561Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.002077Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.004741Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.008064Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.4814Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.4814Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.5443Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.616Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.675Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001949Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.001949Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.4814Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.4814Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.616Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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