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Mammalian Phenotype (MP): abnormal circulating LDL cholesterol level

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   abnormal lipid homeostasis [MP:0002118] <9>(25|29) (29|17|10)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   abnormal sterol level [MP:0012224] <5>(11|13) (14|10|8)
+ + + + 4:   homeostasis/metabolism phenotype [MP:0005376] <7>(140|174) (149|96|44)
+ + + + 4:   abnormal lipid level [MP:0001547] <16>(24|28) (26|16|10)
+ + + + 4:   abnormal cholesterol homeostasis [MP:0005278] <1>(11|12) (13|10|8)
+ + + 3:   abnormal cholesterol level [MP:0003947] <5>(11|12) (13|10|8)
+ + + 3:   abnormal homeostasis [MP:0001764] <27>(103|129) (113|73|31)
+ + + 3:   abnormal circulating lipid level [MP:0003949] <9>(16|23) (19|13|10)
+ + 2:   abnormal lipoprotein level [MP:0010329] <1>(7|8) (8|4|4)
+ + 2:   abnormal blood homeostasis [MP:0009642] <23>(63|82) (70|45|21)
+ + 2:   abnormal circulating cholesterol level [MP:0000180] <4>(9|12) (11|9|8)
+ 1:   abnormal circulating lipoprotein level [MP:0010330] <4>(7|7) (7|4|3)
+ 1:   abnormal circulating non-HDL cholesterol level [MP:0020151] <2>(5|5) (5|4|5)
0:   abnormal circulating LDL cholesterol level [MP:0000181] <2>(5|5) (5|1|0)
- 1:   decreased circulating LDL cholesterol level [MP:0000183](0|0) (0|0|0)
- 1:   increased circulating LDL cholesterol level [MP:0000182](4|4) (4|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Flavoproteins0.00006448Direct
Multidrug efflux transporter AcrB transmembrane domain0.0001144Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0004014Direct
Riboflavin synthase domain-like0.0004014Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Cytochrome p450 reductase N-terminal domain-like0.000001511Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.000006483Direct
NADPH-cytochrome p450 reductase-like0.000006483Direct
Pancreatic lipase, N-terminal domain0.00003643Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Flavoproteins0.00003055Direct
Multidrug efflux transporter AcrB transmembrane domain0.0000559Direct
Riboflavin synthase domain-like0.0002095Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0002095Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
53474,49723
  • 53474 - alpha/beta-Hydrolases
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0.000005221Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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