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Mammalian Phenotype (MP): abnormal triglyceride level

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   homeostasis/metabolism phenotype [MP:0005376] <7>(140|174) (149|96|44)
+ + + 3:   abnormal homeostasis [MP:0001764] <27>(103|129) (113|73|31)
+ + 2:   abnormal lipid homeostasis [MP:0002118] <9>(25|29) (29|17|10)
+ 1:   abnormal lipid level [MP:0001547] <16>(24|28) (26|16|10)
0:   abnormal triglyceride level [MP:0000187] <3>(9|14) (9|9|5)
- 1:   abnormal liver triglyceride level [MP:0012778] <2>(2|2) (2|2|1)
- 1:   decreased triglyceride level [MP:0005318] <2>(3|4) (3|3|1)
- 1:   increased triglyceride level [MP:0005317] <2>(5|7) (5|8|5)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Flavoproteins0.000006884Direct
Apolipoprotein A-I0.00001766Direct
Lipocalins0.08103Inherited
STAT0.1362Inherited
Transcription factor STAT-4 N-domain0.1362Inherited
YWTD domain0.192Inherited
DHS-like NAD/FAD-binding domain0.2859Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Apolipoprotein A-I0Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.000008766Direct
NADPH-cytochrome p450 reductase-like0.000008766Direct
CAD domain0.000448Direct
Pancreatic lipase, N-terminal domain0.05731Inherited
Fatty acid binding protein-like0.09261Inherited
STAT DNA-binding domain0.1034Inherited
STAT0.1034Inherited
Transcription factor STAT-4 N-domain0.1034Inherited
YWTD domain0.1492Inherited
Sir2 family of transcriptional regulators0.236Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain0Direct
Flavoproteins0.000002968Direct
Apolipoprotein A-I0.000007848Direct
Lipocalins0.05987Inherited
STAT0.1067Inherited
Transcription factor STAT-4 N-domain0.1067Inherited
YWTD domain0.1561Inherited
DHS-like NAD/FAD-binding domain0.2435Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.006253Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.1067Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.1067Inherited
    53474,49723
  • 53474 - alpha/beta-Hydrolases
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0.1067Inherited
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.1067Inherited
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.1067Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.1067Inherited
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.2435Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.2731Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.1067Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.1067Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.1067Inherited
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.1067Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.2731Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)