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Mammalian Phenotype (MP): abnormal blood vessel physiology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   cardiovascular system phenotype [MP:0005385] <2>(67|85) (77|57|35)
+ 1:   abnormal cardiovascular system physiology [MP:0001544] <24>(39|45) (46|26|17)
0:   abnormal blood vessel physiology [MP:0000249] <11>(13|17) (15|5|3)
- 1:   pathological neovascularization [MP:0003711] <4>(6|9) (7|4|1)
- 1:   abnormal vascular endothelial cell physiology [MP:0004003] <3>(2|4) (2|0|0)
- 1:   abnormal vascular permeability [MP:0001619] <2>(0|0) (0|0|0)
- 1:   abnormal vascular smooth muscle physiology [MP:0005595] <2>(3|5) (4|1|0)
- 1:   vascular inflammation [MP:0001863] <1>(0|0) (0|0|0)
- 1:   abnormal blood-brain barrier function [MP:0005167](2|0) (2|0|0)
- 1:   abnormal blood-cerebrospinal fluid barrier function [MP:0006088](0|0) (0|0|0)
- 1:   abnormal blood-inner ear barrier function [MP:0004999](0|0) (0|0|0)
- 1:   abnormal carotid body physiology [MP:0003438](0|0) (0|0|0)
- 1:   abnormal vascular wound healing [MP:0004883](3|5) (3|0|0)
- 1:   intramural bleeding in blood vessel wall [MP:0014020](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
YWTD domain0.0005951Direct
Metalloproteases ("zincins"), catalytic domain0.002726Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.01652Inherited
Riboflavin synthase domain-like0.01652Inherited
Flavoproteins0.0324Inherited
PGBD-like0.04943Inherited
Kringle-like0.06592Inherited
Transducin (alpha subunit), insertion domain0.07547Inherited
Nuclear receptor ligand-binding domain0.08997Inherited
Nucleotide cyclase0.1465Inherited
Toll/Interleukin receptor TIR domain0.2916Inherited
Trypsin-like serine proteases0.4892Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Pointed domain0.0001119Direct
YWTD domain0.0004886Direct
Matrix metalloproteases, catalytic domain0.01282Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.02519Inherited
NADPH-cytochrome p450 reductase-like0.02519Inherited
Cytochrome p450 reductase N-terminal domain-like0.02519Inherited
MMP N-terminal domain0.04432Inherited
Transducin (alpha subunit), insertion domain0.06338Inherited
Kringle modules0.06944Inherited
Nuclear receptor ligand-binding domain0.08047Inherited
Nuclear receptor0.08047Inherited
Phosphotyrosine-binding domain (PTB)0.1147Inherited
Adenylyl and guanylyl cyclase catalytic domain0.1279Inherited
Toll/Interleukin receptor TIR domain0.1966Inherited
Forkhead DNA-binding domain0.2284Inherited
Eukaryotic proteases0.4736Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
YWTD domain0.0003155Direct
Metalloproteases ("zincins"), catalytic domain0.001571Inherited
Riboflavin synthase domain-like0.01069Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.01069Inherited
Flavoproteins0.02216Inherited
Family A G protein-coupled receptor-like0.02398Inherited
PGBD-like0.03488Inherited
Kringle-like0.04791Inherited
Transducin (alpha subunit), insertion domain0.05552Inherited
Blood coagulation inhibitor (disintegrin)0.0619Inherited
Nuclear receptor ligand-binding domain0.06715Inherited
Nucleotide cyclase0.1156Inherited
Toll/Interleukin receptor TIR domain0.2489Inherited
Trypsin-like serine proteases0.4415Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.03488Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.05552Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.05552Inherited
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.0619Inherited
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.0619Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.0007431Direct
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.0007431Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.02216Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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