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Mammalian Phenotype (MP): abnormal vascular development

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   cardiovascular system phenotype [MP:0005385] <2>(67|85) (77|57|35)
+ + 2:   abnormal cardiovascular system morphology [MP:0002127] <7>(48|65) (53|44|33)
+ 1:   abnormal cardiovascular development [MP:0002925] <10>(16|35) (25|19|9)
+ 1:   abnormal blood vessel morphology [MP:0001614] <29>(31|38) (36|27|24)
0:   abnormal vascular development [MP:0000259] <9>(13|24) (18|13|5)
- 1:   abnormal angiogenesis [MP:0000260] <8>(9|15) (12|9|4)
- 1:   abnormal vitelline vasculature morphology [MP:0003229] <4>(1|4) (1|0|0)
- 1:   abnormal fetal ductus arteriosus morphology [MP:0010564] <3>(2|2) (2|1|0)
- 1:   abnormal vascular endothelial cell development [MP:0003542] <2>(1|2) (3|2|0)
- 1:   abnormal vasculogenesis [MP:0001622] <1>(0|1) (1|2|1)
- 1:   abnormal blood vessel lumen formation [MP:0020373](0|0) (0|0|0)
- 1:   abnormal perineural vascular plexus morphology [MP:0012732](0|0) (0|0|0)
- 1:   abnormal vascular plexus formation [MP:0013925](1|1) (1|0|0)
- 1:   abnormal vascular smooth muscle development [MP:0011401](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
p53-like transcription factors0.0007652Direct
Frizzled cysteine-rich domain0.08626Inherited
Notch domain0.1032Inherited
Hemopexin-like domain0.1415Inherited
SH3-domain0.1866Inherited
PGBD-like0.2431Inherited
FnI-like domain0.2475Inherited
EGF/Laminin0.2637Inherited
PYP-like sensor domain (PAS domain)0.4616Inherited
Growth factor receptor domain0.513Inherited
Nuclear receptor ligand-binding domain0.5377Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.801Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Pointed domain0.00001105Direct
ets domain0.0001194Direct
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.008851Inherited
Linker histone H1/H50.01029Inherited
Fibronectin type III0.02452Inherited
Transforming growth factor (TGF)-beta0.06643Inherited
Frizzled cysteine-rich domain0.07286Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.08667Inherited
Notch domain0.08667Inherited
ZZ domain0.08667Inherited
NADPH-cytochrome p450 reductase-like0.08667Inherited
Cytochrome p450 reductase N-terminal domain-like0.08667Inherited
DBL homology domain (DH-domain)0.1034Inherited
Integrin beta EGF-like domains0.1233Inherited
Hemopexin-like domain0.1233Inherited
EGF-type module0.1892Inherited
SH3-domain0.2061Inherited
Hypoxia-inducible factor Hif2a, C-terminal domain0.2219Inherited
MMP N-terminal domain0.2219Inherited
Matrix metalloproteases, catalytic domain0.2219Inherited
Growth factor receptor domain0.3328Inherited
Nuclear receptor ligand-binding domain0.5284Inherited
Nuclear receptor0.5284Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
p53-like transcription factors0.0004112Direct
Fibronectin type III0.01693Inherited
Frizzled cysteine-rich domain0.06417Inherited
Notch domain0.07817Inherited
Snake toxin-like0.08997Inherited
DBL homology domain (DH-domain)0.08997Inherited
Hemopexin-like domain0.1112Inherited
SH3-domain0.1511Inherited
PGBD-like0.2034Inherited
FnI-like domain0.2075Inherited
Integrin domains0.2112Inherited
EGF/Laminin0.2224Inherited
PYP-like sensor domain (PAS domain)0.4138Inherited
PH domain-like0.424Inherited
Growth factor receptor domain0.4656Inherited
Nuclear receptor ligand-binding domain0.4906Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.7661Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.002773Inherited
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.04044Inherited
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.04044Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.05575Inherited
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.07817Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.07952Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.08997Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.1112Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.2034Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.2034Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.2917Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.4607Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.004903Inherited
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.07817Inherited
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.1878Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.3069Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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