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Mammalian Phenotype (MP): abnormal angiogenesis

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   cardiovascular system phenotype [MP:0005385] <2>(67|85) (77|57|35)
+ + + 3:   abnormal cardiovascular system morphology [MP:0002127] <7>(48|65) (53|44|33)
+ + 2:   abnormal cardiovascular development [MP:0002925] <10>(16|35) (25|19|9)
+ + 2:   abnormal blood vessel morphology [MP:0001614] <29>(31|38) (36|27|24)
+ 1:   abnormal vascular development [MP:0000259] <9>(13|24) (18|13|5)
0:   abnormal angiogenesis [MP:0000260] <8>(9|15) (12|9|4)
- 1:   abnormal artery development [MP:0003410] <7>(1|3) (3|3|1)
- 1:   abnormal vein development [MP:0003411] <3>(2|2) (2|2|0)
- 1:   abnormal developmental vascular remodeling [MP:0009577] <1>(1|1) (1|1|0)
- 1:   abnormal vascular branching morphogenesis [MP:0003227] <1>(0|0) (0|0|0)
- 1:   abnormal physiological neovascularization [MP:0003710](0|0) (0|0|0)
- 1:   abnormal tumor vascularization [MP:0010144](0|0) (0|0|0)
- 1:   decreased angiogenesis [MP:0005602](2|3) (2|1|2)
- 1:   increased angiogenesis [MP:0005601](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
FnI-like domain0.00002815Direct
Notch domain0.0004453Direct
Nuclear receptor ligand-binding domain0.002854Inherited
PGBD-like0.009207Inherited
Hemopexin-like domain0.01595Inherited
PYP-like sensor domain (PAS domain)0.04531Inherited
EGF/Laminin0.1706Inherited
Growth factor receptor domain0.3823Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Cytochrome p450 reductase N-terminal domain-like0.00008564Direct
Integrin beta EGF-like domains0.0001812Direct
Notch domain0.0003277Direct
NADPH-cytochrome p450 reductase-like0.0003277Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.0003277Direct
Nuclear receptor0.00214Inherited
Nuclear receptor ligand-binding domain0.002831Inherited
Hypoxia-inducible factor Hif2a, C-terminal domain0.00286Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.00286Inherited
MMP N-terminal domain0.00801Inherited
Matrix metalloproteases, catalytic domain0.009826Inherited
Hemopexin-like domain0.01415Inherited
EGF-type module0.1744Inherited
Growth factor receptor domain0.2372Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
FnI-like domain0.00001292Direct
Notch domain0.000234Direct
Integrin domains0.0007952Direct
Nuclear receptor ligand-binding domain0.001653Inherited
PGBD-like0.005713Inherited
Hemopexin-like domain0.01029Inherited
PYP-like sensor domain (PAS domain)0.03178Inherited
p53-like transcription factors0.1182Inherited
EGF/Laminin0.1367Inherited
Snake toxin-like0.1961Inherited
Growth factor receptor domain0.3361Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.00005935Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.000144Direct
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.0002334Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.002643Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.004528Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.005713Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.2565Inherited
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.3953Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.000234Direct
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.0005721Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0006532Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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