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Mammalian Phenotype (MP): abnormal heart development

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   cardiovascular system phenotype [MP:0005385] <2>(67|85) (77|57|35)
+ + 2:   abnormal cardiovascular system morphology [MP:0002127] <7>(48|65) (53|44|33)
+ 1:   abnormal heart morphology [MP:0000266] <22>(27|44) (28|25|19)
+ 1:   abnormal cardiovascular development [MP:0002925] <10>(16|35) (25|19|9)
0:   abnormal heart development [MP:0000267] <10>(5|11) (6|6|4)
- 1:   abnormal heart tube morphology [MP:0000270] <4>(1|3) (1|1|0)
- 1:   abnormal heart looping [MP:0000269] <3>(0|1) (0|1|2)
- 1:   abnormal fetal atrioventricular canal morphology [MP:0006107] <2>(2|4) (3|3|2)
- 1:   abnormal sinus venosus morphology [MP:0003228] <2>(0|0) (0|0|0)
- 1:   abnormal cardiac jelly morphology [MP:0009382] <1>(0|0) (0|0|0)
- 1:   abnormal mesocardium morphology [MP:0010547] <1>(0|0) (0|0|0)
- 1:   abnormal sinuatrial valve morphology [MP:0011646] <1>(0|0) (0|0|0)
- 1:   abnormal endocardial heart tube morphology [MP:0012700](0|0) (0|0|0)
- 1:   abnormal fetal cardiomyocyte morphology [MP:0008788](0|1) (0|1|0)
- 1:   delayed heart development [MP:0012082](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53-like transcription factors0.0003236Direct
SMAD MH1 domain0.0003962Direct
Orange domain-like0.001994Inherited
Growth factor receptor domain0.08579Inherited
Nuclear receptor ligand-binding domain0.2428Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
T-box0.00006927Direct
SMAD MH1 domain0.0002268Direct
SMAD domain0.0002268Direct
Hairy Orange domain0.00135Inherited
Erythroid transcription factor GATA-10.05409Inherited
Transforming growth factor (TGF)-beta0.07558Inherited
Growth factor receptor domain0.08816Inherited
L domain0.1026Inherited
EGF-type module0.1721Inherited
Nuclear receptor ligand-binding domain0.2096Inherited
Nuclear receptor0.2096Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53-like transcription factors0.0001677Direct
SMAD MH1 domain0.0002069Direct
Orange domain-like0.001133Inherited
Growth factor receptor domain0.06374Inherited
Nuclear receptor ligand-binding domain0.2032Inherited
Metalloproteases ("zincins"), catalytic domain0.6888Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.001133Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.09878Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.09878Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.1009Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1247Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.2032Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.01824Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.03746Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.04522Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.09878Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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