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Mammalian Phenotype (MP): abnormal cell morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   mammalian phenotype [MP:0000001] <29>
+ 1:   cellular phenotype [MP:0005384] <6>(95|116) (103|56|31)
0:   abnormal cell morphology [MP:0000358] <12>(19|19) (22|9|2)
- 1:   abnormal cell nucleus morphology [MP:0003111] <9>(3|6) (3|3|0)
- 1:   abnormal mitochondrion morphology [MP:0006035] <8>(1|0) (1|0|0)
- 1:   abnormal germ cell morphology [MP:0002208] <5>(11|12) (13|2|1)
- 1:   abnormal cell mass [MP:0003902] <2>(0|0) (0|0|0)
- 1:   abnormal cilium morphology [MP:0013202] <2>(3|2) (3|3|1)
- 1:   abnormal foam cell morphology [MP:0009840] <2>(0|0) (0|0|0)
- 1:   abnormal plasma membrane morphology [MP:0003950] <2>(0|0) (0|0|0)
- 1:   abnormal lysosome morphology [MP:0005058] <1>(0|0) (1|0|0)
- 1:   abnormal Golgi apparatus morphology [MP:0011743](0|0) (0|0|0)
- 1:   abnormal cell cytoskeleton morphology [MP:0020378](0|0) (0|0|0)
- 1:   abnormal endoplasmic reticulum morphology [MP:0009378](0|0) (0|0|0)
- 1:   abnormal peroxisome morphology [MP:0014010](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
The spindle assembly checkpoint protein mad20Direct
p53 tetramerization domain0Direct
RuvA domain 2-like0.0006114Direct
SMAD MH1 domain0.003817Inherited
Nucleic acid-binding proteins0.004847Inherited
PAZ domain0.009252Inherited
HCP-like0.009252Inherited
WD40 repeat-like0.03016Inherited
Cystine-knot cytokines0.0556Inherited
Tudor/PWWP/MBT0.0822Inherited
Ran binding protein zinc finger-like0.09962Inherited
SMAD/FHA domain0.1504Inherited
Bcl-2 inhibitors of programmed cell death0.2034Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.2223Inherited
Nuclear receptor ligand-binding domain0.2915Inherited
BRCT domain0.309Inherited
BAR/IMD domain-like0.5579Inherited
FAD/NAD(P)-binding domain0.7077Inherited
Cadherin-like0.8292Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
The spindle assembly checkpoint protein mad20Direct
p53 tetramerization domain0Direct
SMAD MH1 domain0.001889Inherited
SMAD domain0.001889Inherited
PAZ domain0.004993Inherited
Single strand DNA-binding domain, SSB0.004993Inherited
Transforming growth factor (TGF)-beta0.0127Inherited
Tudor domain0.01878Inherited
DNA gyrase/MutL, second domain0.03185Inherited
DNA gyrase/MutL, N-terminal domain0.03185Inherited
Tetratricopeptide repeat (TPR)0.05166Inherited
Ran binding protein zinc finger-like0.06578Inherited
Insulin-like0.08142Inherited
DNA replication initiator (cdc21/cdc54) N-terminal domain0.08142Inherited
Bcl-2 inhibitors of programmed cell death0.1547Inherited
Nuclear receptor ligand-binding domain0.2109Inherited
Tandem AAA-ATPase domain0.3908Inherited
Cadherin0.756Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
The spindle assembly checkpoint protein mad20Direct
p53 tetramerization domain0Direct
RuvA domain 2-like0.0003247Direct
SMAD MH1 domain0.002241Inherited
Nucleic acid-binding proteins0.002897Inherited
HCP-like0.005745Inherited
PAZ domain0.005745Inherited
WD40 repeat-like0.02051Inherited
Cystine-knot cytokines0.03966Inherited
Tudor/PWWP/MBT0.06083Inherited
Ran binding protein zinc finger-like0.07512Inherited
Insulin-like0.08965Inherited
dsRNA-binding domain-like0.1135Inherited
SMAD/FHA domain0.1191Inherited
Bcl-2 inhibitors of programmed cell death0.1664Inherited
(Trans)glycosidases0.1815Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1839Inherited
Nuclear receptor ligand-binding domain0.2488Inherited
BRCT domain0.2652Inherited
BAR/IMD domain-like0.5113Inherited
FAD/NAD(P)-binding domain0.6674Inherited
Cadherin-like0.7965Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.00185Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.006293Inherited
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.01422Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.09252Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.1664Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.2755Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.7468Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.6176Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.7087Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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