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Mammalian Phenotype (MP): abnormal mammary gland morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   endocrine/exocrine gland phenotype [MP:0005379] <2>(51|81) (55|36|12)
+ + + 3:   abnormal gland morphology [MP:0002163] <8>(44|71) (50|31|11)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   integument phenotype [MP:0010771] <5>(46|64) (53|34|18)
+ + 2:   abnormal exocrine gland morphology [MP:0013558] <13>(18|22) (19|13|8)
+ 1:   abnormal apocrine gland morphology [MP:0013554] <1>(11|15) (12|11|5)
+ 1:   abnormal skin adnexa morphology [MP:0010678] <12>(21|28) (23|21|10)
0:   abnormal mammary gland morphology [MP:0000627] <17>(11|15) (12|11|5)
- 1:   abnormal mammary gland development [MP:0000628] <9>(3|6) (3|1|0)
- 1:   abnormal nipple morphology [MP:0006078] <9>(0|0) (0|0|0)
- 1:   increased mammary gland tumor incidence [MP:0010299] <6>(1|3) (1|2|0)
- 1:   abnormal mammary gland epithelium morphology [MP:0009504] <4>(2|2) (2|1|0)
- 1:   abnormal mammary gland number [MP:0013714] <3>(0|0) (0|0|0)
- 1:   decreased mammary gland tumor incidence [MP:0010269] <2>(0|0) (0|0|0)
- 1:   abnormal mammary gland lobule morphology [MP:0009505] <1>(4|2) (4|1|0)
- 1:   abnormal abdominal mammary gland morphology [MP:0013710](0|0) (0|0|0)
- 1:   abnormal areola morphology [MP:0009502](0|0) (0|0|0)
- 1:   abnormal cervical mammary gland morphology [MP:0013709](0|0) (0|0|0)
- 1:   abnormal inguinal mammary gland morphology [MP:0013711](0|0) (0|0|0)
- 1:   abnormal mammary gland connective tissue morphology [MP:0009507](0|0) (0|0|0)
- 1:   abnormal mammary gland stroma morphology [MP:0014057](0|0) (0|0|0)
- 1:   abnormal thoracic mammary gland morphology [MP:0013712](0|0) (0|0|0)
- 1:   mammary gland hyperplasia [MP:0000630](0|0) (0|0|0)
- 1:   mammary gland hypoplasia [MP:0003344](1|1) (1|0|0)
- 1:   pale mammary gland [MP:0013719](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
STAT0.0000003331Direct
Transcription factor STAT-4 N-domain0.0000003331Direct
Nuclear receptor coactivator interlocking domain0.0001303Direct
Band 7/SPFH domain0.0006273Direct
4-helical cytokines0.001079Inherited
p53-like transcription factors0.07519Inherited
Nuclear receptor ligand-binding domain0.1213Inherited
EGF/Laminin0.1272Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.4354Inherited
Homeodomain-like0.6485Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
PAS domain of steroid receptor coactivator 1A, NCo-A10Direct
p53 tetramerization domain0Direct
STAT DNA-binding domain0.0000002799Direct
L domain0.0000002799Direct
STAT0.0000002799Direct
Transcription factor STAT-4 N-domain0.0000002799Direct
Nuclear receptor coactivator interlocking domain0.00009797Direct
Long-chain cytokines0.0007276Direct
FHA domain0.02194Inherited
Short-chain cytokines0.0742Inherited
Nuclear receptor ligand-binding domain0.1172Inherited
Nuclear receptor0.1172Inherited
EGF-type module0.1409Inherited
Homeodomain0.5109Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
STAT0.0000001336Direct
Transcription factor STAT-4 N-domain0.0000001336Direct
Nuclear receptor coactivator interlocking domain0.00006448Direct
Band 7/SPFH domain0.0003342Direct
4-helical cytokines0.0005917Direct
SH2 domain0.0007291Direct
p53-like transcription factors0.05532Inherited
Nuclear receptor ligand-binding domain0.09364Inherited
EGF/Laminin0.09871Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.3881Inherited
Homeodomain-like0.6049Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0000001336Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.0000001336Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.0000001336Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.0000001336Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0000001336Direct
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.00004757Direct
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.0009746Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.02236Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.04079Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1673Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0000001336Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.0000001336Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0000001336Direct
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.00002363Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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