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Mammalian Phenotype (MP): abnormal spleen morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + 2:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + 2:   abnormal immune system morphology [MP:0000685] <3>(50|76) (60|35|18)
+ 1:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(57|86) (66|47|21)
+ 1:   abnormal immune system organ morphology [MP:0002722] <8>(21|31) (26|15|9)
0:   abnormal spleen morphology [MP:0000689] <16>(10|15) (12|8|8)
- 1:   abnormal spleen white pulp morphology [MP:0002357] <10>(6|8) (6|6|3)
- 1:   abnormal spleen red pulp morphology [MP:0002356] <3>(1|1) (1|1|3)
- 1:   abnormal spleen size [MP:0002224] <3>(2|7) (5|4|4)
- 1:   abnormal spleen iron level [MP:0008739] <2>(0|0) (0|0|0)
- 1:   abnormal spleen development [MP:0009323] <1>(1|1) (1|0|0)
- 1:   abnormal splenocyte morphology [MP:0009332] <1>(1|1) (1|0|0)
- 1:   abnormal spleen capsule morphology [MP:0002227](0|0) (0|0|0)
- 1:   abnormal spleen perifollicular zone morphology [MP:0010245](0|0) (0|0|0)
- 1:   abnormal spleen trabecular artery morphology [MP:0002354](0|0) (0|0|0)
- 1:   abnormal spleen trabecular vein morphology [MP:0002228](0|0) (0|0|0)
- 1:   abnormal splenic cell ratio [MP:0008826](0|0) (0|0|0)
- 1:   absent spleen [MP:0000690](0|0) (0|0|0)
- 1:   accessory spleen [MP:0003342](0|0) (0|0|0)
- 1:   pale spleen [MP:0009246](0|0) (0|0|0)
- 1:   spleen fibrosis [MP:0011746](0|0) (0|0|0)
- 1:   spleen vascular congestion [MP:0010020](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
SPOC domain-like0Direct
SH2 domain0.0009334Direct
DEATH domain0.006318Inherited
TNF-like0.01118Inherited
CCCH zinc finger0.01481Inherited
TNF receptor-like0.02054Inherited
WWE domain0.06592Inherited
Notch domain0.06592Inherited
Caspase-like0.1209Inherited
Homeodomain-like0.9628Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
SH2 domain0.000752Direct
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.001933Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.004193Inherited
Nuclear receptor coactivator interlocking domain0.005302Inherited
TNF-like0.008474Inherited
CCCH zinc finger0.01082Inherited
DEATH domain, DD0.01527Inherited
Interferon regulatory factor 3 (IRF3), transactivation domain0.02063Inherited
TNF receptor-like0.02685Inherited
Notch domain0.05207Inherited
WWE domain0.05207Inherited
Bcl-2 inhibitors of programmed cell death0.06998Inherited
Hypoxia-inducible factor Hif2a, C-terminal domain0.06998Inherited
Pyrin domain, PYD0.1343Inherited
Homeodomain1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SPOC domain-like0Direct
SH2 domain0.0005069Direct
DEATH domain0.003839Inherited
Nuclear receptor coactivator interlocking domain0.004544Inherited
TNF-like0.007045Inherited
CCCH zinc finger0.0095Inherited
TNF receptor-like0.01351Inherited
WWE domain0.04791Inherited
Notch domain0.04791Inherited
Bcl-2 inhibitors of programmed cell death0.06397Inherited
Caspase-like0.09323Inherited
Homeodomain-like0.9429Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.001326Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.003536Inherited
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.02154Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0403Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.05639Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.1085Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.1247Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.01824Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.03222Inherited
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.04791Inherited
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.04791Inherited
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.04791Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.1006Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.1987Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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