SUPERFAMILY 1.75 HMM library and genome assignments server

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Mammalian Phenotype (MP): enlarged spleen

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   mammalian phenotype [MP:0000001] <29>
+ + + + + 5:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + 4:   abnormal immune system morphology [MP:0000685] <3>(50|76) (60|35|18)
+ + + + 4:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + 3:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(57|86) (66|47|21)
+ + + 3:   abnormal immune system organ morphology [MP:0002722] <8>(21|31) (26|15|9)
+ + 2:   abnormal lymph organ size [MP:0002221] <5>(7|16) (10|10|5)
+ + 2:   abnormal spleen morphology [MP:0000689] <16>(10|15) (12|8|8)
+ 1:   abnormal spleen size [MP:0002224] <3>(2|7) (5|4|4)
0:   enlarged spleen [MP:0000691] <2>(2|6) (5|3|4)
- 1:   increased spleen weight [MP:0004952](0|0) (0|0|0)
- 1:   spleen hyperplasia [MP:0000693](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
TNF receptor-like0.0000282Direct
CCCH zinc finger0.0005949Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
TNF receptor-like0.00003164Direct
Pyrin domain, PYD0.00023Direct
CCCH zinc finger0.0004444Direct
Notch domain0.0007438Direct
Nuclear receptor coactivator interlocking domain0.0007438Direct
Bcl-2 inhibitors of programmed cell death0.0009396Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
TNF receptor-like0.00001295Direct
CCCH zinc finger0.0003153Direct
Nuclear receptor coactivator interlocking domain0.0005775Direct
Notch domain0.0005775Direct
Bcl-2 inhibitors of programmed cell death0.0007022Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.00002363Direct
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.00005844Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.0001537Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0001537Direct
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0001537Direct
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.000507Direct
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0005775Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)