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Mammalian Phenotype (MP): abnormal thymus morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + 3:   endocrine/exocrine gland phenotype [MP:0005379] <2>(51|81) (55|36|12)
+ + 2:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + 2:   abnormal gland morphology [MP:0002163] <8>(44|71) (50|31|11)
+ + 2:   abnormal immune system morphology [MP:0000685] <3>(51|76) (60|35|18)
+ 1:   abnormal immune system organ morphology [MP:0002722] <8>(21|31) (26|15|9)
+ 1:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(58|86) (66|47|21)
+ 1:   abnormal endocrine gland morphology [MP:0013560] <7>(16|29) (21|19|4)
0:   abnormal thymus morphology [MP:0000703] <14>(10|16) (12|10|2)
- 1:   decreased thymocyte number [MP:0000715] <4>(2|4) (4|2|1)
- 1:   increased thymocyte number [MP:0000714] <4>(0|0) (0|0|0)
- 1:   abnormal thymus epithelium morphology [MP:0009544] <3>(2|2) (2|1|0)
- 1:   abnormal thymus lobule morphology [MP:0002367] <3>(4|5) (4|3|0)
- 1:   abnormal thymus size [MP:0002364] <3>(1|5) (1|6|1)
- 1:   abnormal thymus development [MP:0000704] <1>(3|3) (3|1|0)
- 1:   abnormal thymus capsule morphology [MP:0002368](0|0) (0|0|0)
- 1:   abnormal thymus cell ratio [MP:0008827](0|0) (0|0|0)
- 1:   abnormal thymus topology [MP:0013936](0|0) (0|0|0)
- 1:   abnormal thymus trabecula morphology [MP:0002370](0|0) (0|0|0)
- 1:   athymia [MP:0000705](1|1) (1|0|0)
- 1:   ectopic thymus [MP:0003007](1|1) (1|0|0)
- 1:   thymus cysts [MP:0014130](0|0) (0|0|0)
- 1:   thymus fibrosis [MP:0014129](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
SH2 domain0.000005474Direct
p53-like transcription factors0.00001343Direct
E set domains0.006198Inherited
Nuclear receptor ligand-binding domain0.006206Inherited
CCCH zinc finger0.009811Inherited
TNF-like0.02534Inherited
Cysteine-rich domain0.02822Inherited
TNF receptor-like0.03532Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.06101Inherited
Homeodomain-like0.09472Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
SH2 domain0.000005297Direct
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.0001531Direct
Rel/Dorsal transcription factors, DNA-binding domain0.0005358Direct
DEATH domain, DD0.0006735Direct
Linker histone H1/H50.0012Inherited
Nuclear receptor0.00363Inherited
Nuclear receptor ligand-binding domain0.005118Inherited
CCCH zinc finger0.007274Inherited
TNF receptor-like0.008982Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.01357Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.01362Inherited
TNF-like0.0208Inherited
Pointed domain0.02305Inherited
E2F dimerization segment0.02305Inherited
ets domain0.06709Inherited
Homeodomain0.2068Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SH2 domain0.000002347Direct
p53-like transcription factors0.000005946Direct
Protein kinase-like (PK-like)0.001044Inherited
E set domains0.003763Inherited
Nuclear receptor ligand-binding domain0.003768Inherited
CCCH zinc finger0.006124Inherited
TNF-like0.01695Inherited
Cysteine-rich domain0.01907Inherited
TNF receptor-like0.02431Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.04402Inherited
Homeodomain-like0.07106Inherited
beta-beta-alpha zinc fingers0.1151Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54236,57889
  • 54236 - Ubiquitin-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.0000006353Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.0004121Direct
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.001173Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.001857Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.004603Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.006433Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.006524Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.123Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.01135Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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