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Mammalian Phenotype (MP): abnormal brain development

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   nervous system phenotype [MP:0003631] <2>(98|128) (113|79|50)
+ + 2:   abnormal nervous system morphology [MP:0003632] <17>(76|104) (91|64|47)
+ 1:   abnormal brain morphology [MP:0002152] <24>(25|42) (35|24|14)
+ 1:   abnormal nervous system development [MP:0003861] <9>(19|31) (21|14|10)
0:   abnormal brain development [MP:0000913] <15>(6|12) (7|4|1)
- 1:   abnormal hindbrain development [MP:0006108] <4>(1|3) (1|2|1)
- 1:   abnormal forebrain development [MP:0003232] <2>(3|5) (3|1|0)
- 1:   abnormal midbrain-hindbrain boundary morphology [MP:0012132] <2>(1|1) (1|0|0)
- 1:   abnormal rhombic lip morphology [MP:0012525] <2>(0|0) (0|0|0)
- 1:   holoprosencephaly [MP:0005157] <2>(0|1) (0|0|0)
- 1:   hydroencephaly [MP:0001891] <2>(1|2) (1|0|0)
- 1:   abnormal midbrain development [MP:0003864] <1>(0|0) (0|0|0)
- 1:   abnormal olfactory bulb development [MP:0002739] <1>(3|2) (3|1|0)
- 1:   abnormal cervical flexure morphology [MP:0010744](0|0) (0|0|0)
- 1:   abnormal embryonic neuroepithelial layer differentiation [MP:0000786](0|0) (0|0|0)
- 1:   abnormal primordial meninx morphology [MP:0009726](0|0) (0|0|0)
- 1:   decreased oligodendrocyte progenitor number [MP:0000954](0|0) (0|0|0)
- 1:   delayed brain development [MP:0001889](0|0) (0|0|0)
- 1:   exencephaly [MP:0000914](1|2) (1|0|0)
- 1:   increased oligodendrocyte progenitor number [MP:0010892](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Homeodomain-like0.03243Inherited
HLH, helix-loop-helix DNA-binding domain0.1008Inherited
Growth factor receptor domain0.1349Inherited
EGF/Laminin0.1788Inherited
Family A G protein-coupled receptor-like0.9426Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Mib/herc2 domain0.0007792Direct
Classic zinc finger, C2H20.0008423Direct
Cyclin0.006855Inherited
Enabled/VASP homology 1 domain (EVH1 domain)0.007236Inherited
DIX domain0.04505Inherited
Homeodomain0.04718Inherited
Forkhead DNA-binding domain0.06483Inherited
HLH, helix-loop-helix DNA-binding domain0.0859Inherited
Phosphotyrosine-binding domain (PTB)0.1532Inherited
POU-specific domain0.328Inherited
Rhodopsin-like0.9141Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Mib/herc2 domain-like0.0006408Direct
Homeodomain-like0.02218Inherited
HLH, helix-loop-helix DNA-binding domain0.07617Inherited
Growth factor receptor domain0.1055Inherited
EGF/Laminin0.1441Inherited
Family A G protein-coupled receptor-like0.9203Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.02624Inherited
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.05427Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.3147Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.5589Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.5589Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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