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Mammalian Phenotype (MP): abnormal testis morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   reproductive system phenotype [MP:0005389] <2>(38|58) (47|18|6)
+ + + + 4:   endocrine/exocrine gland phenotype [MP:0005379] <2>(51|81) (55|36|12)
+ + + 3:   abnormal male reproductive system morphology [MP:0001145] <2>(12|18) (15|4|0)
+ + + 3:   abnormal reproductive system morphology [MP:0002160] <12>(28|46) (37|15|6)
+ + + 3:   abnormal gland morphology [MP:0002163] <8>(44|71) (50|31|11)
+ + 2:   abnormal sex gland morphology [MP:0000653] <5>(20|29) (23|10|2)
+ + 2:   abnormal male genitalia morphology [MP:0009198] <2>(12|18) (15|4|0)
+ 1:   abnormal internal male genitalia morphology [MP:0009205] <10>(12|17) (15|4|0)
+ 1:   abnormal male reproductive gland morphology [MP:0013325] <4>(10|15) (12|4|0)
0:   abnormal testis morphology [MP:0001146] <15>(9|15) (11|4|0)
- 1:   abnormal seminiferous tubule morphology [MP:0002216] <6>(2|5) (3|1|0)
- 1:   abnormal testis size [MP:0004849] <3>(5|9) (6|2|0)
- 1:   abnormal efferent ductules of testis morphology [MP:0004728] <2>(1|0) (1|0|0)
- 1:   abnormal rete testis morphology [MP:0006416] <2>(0|0) (0|0|0)
- 1:   abnormal testis development [MP:0003830] <2>(0|0) (0|0|0)
- 1:   abnormal testis interstitial tissue morphology [MP:0011416](0|0) (0|0|0)
- 1:   abnormal testis tunica albuginea morphology [MP:0013738](0|0) (0|0|0)
- 1:   abnormal testis tunica vaginalis morphology [MP:0013739](0|0) (0|0|0)
- 1:   absent testes [MP:0006415](0|1) (1|0|0)
- 1:   cryptorchism [MP:0002286](1|1) (1|0|0)
- 1:   ectopic testis [MP:0011410](0|0) (0|0|0)
- 1:   hydrocele [MP:0003623](0|0) (0|0|0)
- 1:   increased testis apoptosis [MP:0013601](0|0) (0|0|0)
- 1:   testis degeneration [MP:0013600](0|0) (0|0|0)
- 1:   testis fibrosis [MP:0014189](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
E2F-DP heterodimerization region0.00003459Direct
PAZ domain0.0001076Direct
The spindle assembly checkpoint protein mad20.0005961Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.001175Inherited
HMG-box0.03497Inherited
Tudor/PWWP/MBT0.1821Inherited
LDL receptor-like module0.5533Inherited
Nuclear receptor ligand-binding domain0.5756Inherited
Homeodomain-like0.863Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
E2F dimerization segment0.000003676Direct
PAZ domain0.00006478Direct
Cell cycle transcription factor e2f-dp0.0001583Direct
The spindle assembly checkpoint protein mad20.0003663Direct
DNA gyrase/MutL, second domain0.0003663Direct
DNA gyrase/MutL, N-terminal domain0.0003663Direct
Single strand DNA-binding domain, SSB0.0004744Direct
Gonadodropin/Follitropin0.001322Inherited
Cysteine-rich DNA binding domain, (DM domain)0.005742Inherited
HMG-box0.02774Inherited
Tudor domain0.312Inherited
LDL receptor-like module0.5262Inherited
Nuclear receptor ligand-binding domain0.5591Inherited
Nuclear receptor0.6387Inherited
Homeodomain0.8592Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
E2F-DP heterodimerization region0.00001597Direct
PAZ domain0.00005223Direct
The spindle assembly checkpoint protein mad20.0003162Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.0006465Direct
Ribonuclease H-like0.004053Inherited
Cysteine-rich DNA binding domain, (DM domain)0.005037Inherited
HMG-box0.02406Inherited
Tudor/PWWP/MBT0.1471Inherited
LDL receptor-like module0.5065Inherited
Nuclear receptor ligand-binding domain0.5292Inherited
Homeodomain-like0.833Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.00001597Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.001145Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.001145Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.5747Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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