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Mammalian Phenotype (MP): abnormal spermatogenesis

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   reproductive system phenotype [MP:0005389] <2>(38|58) (47|18|6)
+ + 2:   abnormal reproductive system morphology [MP:0002160] <12>(28|46) (37|15|6)
+ 1:   abnormal gametogenesis [MP:0001929] <7>(15|19) (19|3|1)
0:   abnormal spermatogenesis [MP:0001156] <10>(8|13) (11|3|0)
- 1:   abnormal male meiosis [MP:0005169] <3>(3|4) (3|1|0)
- 1:   abnormal spermiogenesis [MP:0001932] <3>(2|4) (4|1|0)
- 1:   arrest of spermatogenesis [MP:0001155] <2>(1|3) (1|0|0)
- 1:   teratozoospermia [MP:0005578] <2>(1|0) (1|0|0)
- 1:   abnormal spermatid morphology [MP:0006380] <1>(0|0) (0|0|0)
- 1:   abnormal spermatocyte morphology [MP:0006379](0|0) (0|0|0)
- 1:   abnormal spermatogonia proliferation [MP:0002685](0|0) (0|0|0)
- 1:   azoospermia [MP:0005159](1|1) (2|0|0)
- 1:   necrospermia [MP:0009325](0|0) (0|0|0)
- 1:   oligozoospermia [MP:0002687](0|0) (1|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
PAZ domain0.00007385Direct
The spindle assembly checkpoint protein mad20.0004621Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.004834Inherited
Cysteine-rich DNA binding domain, (DM domain)0.006566Inherited
Ribosomal protein S5 domain 2-like0.03943Inherited
SAICAR synthase-like0.04609Inherited
BAR/IMD domain-like0.2826Inherited
Fibronectin type III0.6057Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
PAZ domain0.00003578Direct
The spindle assembly checkpoint protein mad20.0002469Direct
DNA gyrase/MutL, second domain0.0002469Direct
DNA gyrase/MutL, N-terminal domain0.0002469Direct
Single strand DNA-binding domain, SSB0.0002944Direct
Gonadodropin/Follitropin0.0009042Direct
Cysteine-rich DNA binding domain, (DM domain)0.004058Inherited
Tudor domain0.294Inherited
PHD domain0.4009Inherited
Protein kinases, catalytic subunit0.4237Inherited
Fibronectin type III0.5473Inherited
Histone lysine methyltransferases0.821Inherited
I set domains0.8535Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
PAZ domain0.0000353Direct
The spindle assembly checkpoint protein mad20.0002426Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.002888Inherited
Cysteine-rich DNA binding domain, (DM domain)0.004Inherited
dsRNA-binding domain-like0.01844Inherited
Ribosomal protein S5 domain 2-like0.02731Inherited
SAICAR synthase-like0.03239Inherited
BAR/IMD domain-like0.2404Inherited
Fibronectin type III0.5603Inherited
Tudor/PWWP/MBT0.5794Inherited
Immunoglobulin0.9929Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.0008943Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0008943Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.6499Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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