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Mammalian Phenotype (MP): decreased body weight

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   growth/size/body region phenotype [MP:0005378] <12>(64|95) (71|47|27)
+ + + 3:   abnormal body composition [MP:0005451] <5>(20|31) (24|15|9)
+ + + 3:   abnormal postnatal growth/weight/body size [MP:0002089] <3>(37|51) (41|31|14)
+ + 2:   abnormal total tissue mass [MP:0012321] <2>(16|26) (19|12|6)
+ + 2:   abnormal body size [MP:0003956] <5>(27|40) (30|19|7)
+ 1:   decreased body size [MP:0001265] <6>(11|21) (12|10|3)
+ 1:   abnormal body weight [MP:0001259] <4>(21|28) (24|14|7)
+ 1:   decreased total tissue mass [MP:0012322] <1>(6|12) (7|6|3)
0:   decreased body weight [MP:0001262] <2>(6|11) (7|6|3)
- 1:   weight loss [MP:0001263] <1>(3|4) (3|2|0)
- 1:   slow postnatal weight gain [MP:0008489](1|2) (2|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
N-acetylmuramoyl-L-alanine amidase-like0Direct
Guanido kinase N-terminal domain0Direct
FtsH protease domain-like0Direct
p53 tetramerization domain0Direct
Acid proteases0.05596Inherited
Clathrin adaptor appendage domain0.2209Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
Guanido kinase catalytic domain0Direct
Retinoblastoma tumor suppressor domains0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
RUNT domain0Direct
p53 tetramerization domain0Direct
Guanido kinase N-terminal domain0Direct
FtsH protease domain-like0Direct
Pepsin-like0.003328Inherited
gamma-adaptin C-terminal appendage domain-like0.01127Inherited
VHS domain0.1056Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
FtsH protease domain-like0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
p53 tetramerization domain0Direct
Guanido kinase N-terminal domain0Direct
ENTH/VHS domain0.005741Inherited
Acid proteases0.03995Inherited
Clathrin adaptor appendage domain0.1826Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    52540,140990
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 140990 - FtsH protease domain-like
  • 0Direct
    48034,55931
  • 48034 - Guanido kinase N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 0Direct
    54236,57889
  • 54236 - Ubiquitin-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.1353Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57850,49599,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0Direct
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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