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Mammalian Phenotype (MP): abnormal eye development

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   vision/eye phenotype [MP:0005391] <2>(43|53) (50|27|17)
+ 1:   abnormal eye morphology [MP:0002092] <23>(39|49) (46|25|15)
0:   abnormal eye development [MP:0001286] <22>(6|5) (6|2|2)
- 1:   abnormal lens development [MP:0005545] <4>(1|2) (1|0|0)
- 1:   coloboma [MP:0005262] <4>(1|2) (2|1|0)
- 1:   abnormal primary vitreous morphology [MP:0009620] <2>(2|2) (2|1|0)
- 1:   abnormal eyelid development [MP:0009651] <1>(0|0) (0|0|0)
- 1:   abnormal hyaloid artery morphology [MP:0012537] <1>(0|0) (0|0|0)
- 1:   abnormal optic cup morphology [MP:0004269] <1>(0|0) (0|0|0)
- 1:   abnormal optic fissure closure [MP:0012535] <1>(0|0) (0|0|0)
- 1:   abnormal optic vesicle formation [MP:0003425] <1>(1|1) (1|0|0)
- 1:   abnormal retinal development [MP:0009772] <1>(1|0) (1|0|1)
- 1:   persistent hyaloid artery [MP:0012538] <1>(0|0) (0|0|0)
- 1:   abnormal corneal stroma development [MP:0003095](0|0) (0|0|0)
- 1:   abnormal eye muscle development [MP:0003818](0|0) (0|0|0)
- 1:   abnormal optic eminence morphology [MP:0006305](0|0) (0|0|0)
- 1:   abnormal optic fissure morphology [MP:0012534](0|0) (0|0|0)
- 1:   abnormal optic stalk morphology [MP:0004268](0|0) (0|0|0)
- 1:   abnormal periocular mesenchyme morphology [MP:0004054](0|0) (0|0|0)
- 1:   aniridia [MP:0005261](0|0) (0|0|0)
- 1:   cyclopia [MP:0005163](0|0) (0|0|0)
- 1:   ectopia lentis [MP:0005263](0|0) (0|0|0)
- 1:   eye bleb [MP:0008855](0|0) (0|0|0)
- 1:   lenticonus [MP:0002794](0|0) (0|0|0)
- 1:   persistence of hyaloid vascular system [MP:0001289](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nuclear receptor ligand-binding domain0.0005575Direct
E2F-DP heterodimerization region0.0008219Direct
Homeodomain-like0.001035Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.001133Inherited
Toll/Interleukin receptor TIR domain0.0383Inherited
gamma-Crystallin-like0.136Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
E2F dimerization segment0.0002803Direct
Nuclear receptor ligand-binding domain0.0003928Direct
Nuclear receptor0.0003928Direct
Homeodomain0.00228Inherited
Crystallins/Ca-binding development proteins0.1178Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nuclear receptor ligand-binding domain0.0002959Direct
E2F-DP heterodimerization region0.0004441Direct
Homeodomain-like0.0005662Direct
Glucocorticoid receptor-like (DNA-binding domain)0.0006233Direct
Toll/Interleukin receptor TIR domain0.02649Inherited
gamma-Crystallin-like0.1065Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.0004441Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.001025Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0000872Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.09669Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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