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Mammalian Phenotype (MP): abnormal blood vessel morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   cardiovascular system phenotype [MP:0005385] <2>(67|85) (77|57|35)
+ 1:   abnormal cardiovascular system morphology [MP:0002127] <7>(48|65) (53|44|33)
0:   abnormal blood vessel morphology [MP:0001614] <29>(31|38) (36|27|24)
- 1:   abnormal vein morphology [MP:0002725] <17>(2|2) (2|4|2)
- 1:   abnormal artery morphology [MP:0002191] <10>(17|20) (19|16|17)
- 1:   abnormal vascular development [MP:0000259] <9>(13|24) (18|13|5)
- 1:   abnormal kidney blood vessel morphology [MP:0000530] <7>(5|5) (5|0|0)
- 1:   abnormal capillary morphology [MP:0003658] <6>(5|5) (5|0|0)
- 1:   abnormal vascular smooth muscle morphology [MP:0005592] <6>(0|0) (1|1|0)
- 1:   abnormal blood vessel endothelium morphology [MP:0009489] <4>(0|1) (0|0|0)
- 1:   abnormal retinal vasculature morphology [MP:0002792] <4>(4|3) (4|3|1)
- 1:   arteriovenous malformation [MP:0006093] <4>(0|0) (0|1|1)
- 1:   vasculature congestion [MP:0000255] <4>(4|5) (4|0|1)
- 1:   abnormal intersomitic vessel morphology [MP:0012253] <3>(1|0) (2|0|0)
- 1:   abnormal liver vasculature morphology [MP:0009820] <3>(4|4) (4|0|0)
- 1:   abnormal lung vasculature morphology [MP:0004007] <3>(4|4) (4|0|0)
- 1:   vascular stenosis [MP:0005412] <3>(0|0) (0|0|1)
- 1:   abnormal choroid vasculature morphology [MP:0006237] <2>(3|2) (3|2|1)
- 1:   abnormal placenta vasculature [MP:0003231] <2>(1|2) (1|0|0)
- 1:   abnormal blood vessel elastic tissue morphology [MP:0006083] <1>(0|2) (0|3|2)
- 1:   abnormal conjunctival vasculature morphology [MP:0006192] <1>(0|0) (0|0|0)
- 1:   abnormal cranial blood vasculature morphology [MP:0014012] <1>(0|0) (0|0|0)
- 1:   dilated vasculature [MP:0004938] <1>(0|1) (0|0|0)
- 1:   abnormal pericyte morphology [MP:0003719](0|0) (0|0|0)
- 1:   abnormal perivascular macrophage morphology [MP:0008242](0|0) (0|0|0)
- 1:   abnormal stria vascularis vasculature morphology [MP:0004368](0|0) (0|0|0)
- 1:   abnormal urinary bladder blood vessel morphology [MP:0011773](0|0) (0|0|0)
- 1:   atretic vasculature [MP:0000265](0|0) (0|0|0)
- 1:   hemangioma [MP:0014086](0|0) (0|0|0)
- 1:   perivascular fibrosis [MP:0011749](4|4) (4|0|0)
- 1:   vascular diverticulum [MP:0013869](0|0) (0|0|0)
- 1:   vasculature degeneration [MP:0012562](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
EGF/Laminin0.00001502Direct
Calcium-dependent phosphotriesterase0.000168Direct
Integrin beta tail domain0.0007566Direct
Notch domain0.0008758Direct
FnI-like domain0.005419Inherited
YWTD domain0.0107Inherited
Cytokine0.01581Inherited
Integrin domains0.02235Inherited
Growth factor receptor domain0.02983Inherited
p53-like transcription factors0.03431Inherited
Tetraspanin0.05048Inherited
PYP-like sensor domain (PAS domain)0.06176Inherited
PGBD-like0.08562Inherited
Hemopexin-like domain0.1175Inherited
Metalloproteases ("zincins"), catalytic domain0.1715Inherited
Homeodomain-like0.1903Inherited
TB module/8-cys domain0.2193Inherited
Nuclear receptor ligand-binding domain0.237Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.2944Inherited
Interleukin 8-like chemokines0.2954Inherited
Kringle-like0.2961Inherited
Flavoproteins0.2979Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.3452Inherited
Riboflavin synthase domain-like0.3452Inherited
Frizzled cysteine-rich domain0.3627Inherited
E set domains0.3686Inherited
Snake toxin-like0.3696Inherited
SH3-domain0.4818Inherited
Trypsin-like serine proteases0.7571Inherited
Protein kinase-like (PK-like)0.9547Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Interleukin-1 (IL-1)0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Integrin beta EGF-like domains0.0001141Direct
Pointed domain0.0005413Direct
Integrin beta tail domain0.0005413Direct
Notch domain0.0006108Direct
EGF-type module0.001083Inherited
Erythroid transcription factor GATA-10.001528Inherited
Hypoxia-inducible factor Hif2a, C-terminal domain0.001805Inherited
YWTD domain0.008838Inherited
ets domain0.01378Inherited
Integrin domains0.01794Inherited
Forkhead DNA-binding domain0.019Inherited
Transforming growth factor (TGF)-beta0.04753Inherited
Fibroblast growth factors (FGF)0.07202Inherited
MMP N-terminal domain0.07202Inherited
Matrix metalloproteases, catalytic domain0.07202Inherited
Linker histone H1/H50.07841Inherited
Hemopexin-like domain0.1011Inherited
DBL homology domain (DH-domain)0.1218Inherited
Homeodomain0.1264Inherited
TB module/8-cys domain0.1957Inherited
ZZ domain0.1957Inherited
Nuclear receptor ligand-binding domain0.2272Inherited
Nuclear receptor0.2272Inherited
Fibronectin type III0.2284Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.2719Inherited
NADPH-cytochrome p450 reductase-like0.2719Inherited
Cytochrome p450 reductase N-terminal domain-like0.2719Inherited
Interleukin 8-like chemokines0.2875Inherited
Growth factor receptor domain0.3122Inherited
Kringle modules0.3228Inherited
Frizzled cysteine-rich domain0.3438Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.4114Inherited
Eukaryotic proteases0.4195Inherited
SH3-domain0.5237Inherited
LIM domain0.8377Inherited
Protein kinases, catalytic subunit0.8932Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
EGF/Laminin0.000006661Direct
Calcium-dependent phosphotriesterase0.0000842Direct
Integrin beta tail domain0.0004066Direct
Notch domain0.0004739Direct
FnI-like domain0.003257Inherited
YWTD domain0.006716Inherited
Cytokine0.01019Inherited
Integrin domains0.01479Inherited
Growth factor receptor domain0.02028Inherited
p53-like transcription factors0.02356Inherited
Tetraspanin0.03566Inherited
PYP-like sensor domain (PAS domain)0.04459Inherited
PGBD-like0.06361Inherited
4-helical cytokines0.07129Inherited
Hemopexin-like domain0.09052Inherited
DBL homology domain (DH-domain)0.09641Inherited
Metalloproteases ("zincins"), catalytic domain0.1375Inherited
Homeodomain-like0.1545Inherited
Fibronectin type III0.1669Inherited
TB module/8-cys domain0.1811Inherited
Nuclear receptor ligand-binding domain0.1977Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.2515Inherited
Interleukin 8-like chemokines0.2524Inherited
Kringle-like0.2529Inherited
Flavoproteins0.2548Inherited
Riboflavin synthase domain-like0.2999Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.2999Inherited
Frizzled cysteine-rich domain0.3169Inherited
E set domains0.3228Inherited
Snake toxin-like0.3237Inherited
Ankyrin repeat0.4274Inherited
SH3-domain0.4341Inherited
Trypsin-like serine proteases0.7191Inherited
PH domain-like0.8456Inherited
Protein kinase-like (PK-like)0.9338Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0000006531Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.000001183Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.000002155Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.0002656Direct
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.0004066Direct
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0.0004066Direct
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.0004066Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.001156Inherited
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.001888Inherited
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.001888Inherited
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.002577Inherited
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.002577Inherited
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.004701Inherited
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.004701Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.005211Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.01019Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.02148Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.0553Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.06361Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.07714Inherited
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.1283Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.2303Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.2529Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.275Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.7521Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.00001081Direct
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.0000842Direct
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.0000842Direct
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0000862Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0001404Direct
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.0004066Direct
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0004066Direct
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.0004066Direct
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.0004739Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0004739Direct
    57196,57196,57581
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.0004739Direct
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0004739Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0007167Direct
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.001888Inherited
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.001888Inherited
    57196,57581,57184
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0.002481Inherited
    57581,57196,57581
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.008207Inherited
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.01759Inherited
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.1811Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.2303Inherited
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2548Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.6386Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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