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Mammalian Phenotype (MP): abnormal induced morbidity/mortality

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   mammalian phenotype [MP:0000001] <29>
+ 1:   mortality/aging [MP:0010768] <4>(83|115) (89|67|50)
0:   abnormal induced morbidity/mortality [MP:0001657] <5>(21|23) (21|9|3)
- 1:   abnormal sensitivity to induced morbidity/mortality [MP:0020148] <3>(16|20) (16|9|3)
- 1:   abnormal susceptibility to colitis induced morbidity/mortality [MP:0013297] <2>(0|0) (0|0|0)
- 1:   abnormal xenobiotic induced morbidity/mortality [MP:0009765] <2>(1|1) (1|0|0)
- 1:   altered susceptibility to infection induced morbidity/mortality [MP:0009785] <2>(2|2) (2|1|0)
- 1:   abnormal susceptibility to injury induced morbidity/mortality [MP:0020344](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
WGR domain-like0Direct
4-helical cytokines0.000007167Direct
DEATH domain0.00001735Direct
Toll/Interleukin receptor TIR domain0.00005602Direct
C-type lectin-like0.00005868Direct
Domain of poly(ADP-ribose) polymerase0.0005744Direct
Flavoproteins0.0007175Direct
Riboflavin synthase domain-like0.000877Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.000877Direct
Alpha-macroglobulin receptor domain0.0009336Direct
GroES-like0.004424Inherited
Terpenoid cyclases/Protein prenyltransferases0.01533Inherited
Nuclear receptor ligand-binding domain0.01691Inherited
Caspase-like0.02518Inherited
Ran binding protein zinc finger-like0.02719Inherited
BRCT domain0.03967Inherited
Immunoglobulin0.06775Inherited
ADP-ribosylation0.07751Inherited
SMAD/FHA domain0.2557Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
WGR domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
C-type lectin domain0.000008129Direct
NADPH-cytochrome p450 reductase-like0.00004442Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.00004442Direct
Toll/Interleukin receptor TIR domain0.0002278Direct
Domain of poly(ADP-ribose) polymerase0.0004088Direct
Tissue inhibitor of metalloproteinases, TIMP0.0004088Direct
Complement components0.0006523Direct
Alpha-macroglobulin receptor domain0.0006523Direct
Fibronectin type II module0.001645Inherited
Alcohol dehydrogenase-like, N-terminal domain0.003402Inherited
Alcohol dehydrogenase-like, C-terminal domain0.003402Inherited
Poly(ADP-ribose) polymerase, C-terminal domain0.01046Inherited
Nuclear receptor ligand-binding domain0.01558Inherited
Nuclear receptor0.01558Inherited
Caspase catalytic domain0.02069Inherited
Ran binding protein zinc finger-like0.0238Inherited
FHA domain0.06151Inherited
Caspase recruitment domain, CARD0.06151Inherited
PHD domain0.353Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
WGR domain-like0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
4-helical cytokines0.000003096Direct
DEATH domain0.000007721Direct
Toll/Interleukin receptor TIR domain0.00002637Direct
C-type lectin-like0.00002774Direct
Domain of poly(ADP-ribose) polymerase0.0003044Direct
Flavoproteins0.0003847Direct
Riboflavin synthase domain-like0.0004748Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0004748Direct
Alpha-macroglobulin receptor domain0.0005072Direct
GroES-like0.00262Inherited
Terpenoid cyclases/Protein prenyltransferases0.009865Inherited
Nuclear receptor ligand-binding domain0.01097Inherited
Caspase-like0.01684Inherited
Ran binding protein zinc finger-like0.0183Inherited
BRCT domain0.02751Inherited
Immunoglobulin0.04938Inherited
ADP-ribosylation0.05705Inherited
SMAD/FHA domain0.215Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
142921,47587
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 0Direct
    51735,50129
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 0Direct
    47587,56399
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0.0003044Direct
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.002015Inherited
    50129,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.00262Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.01864Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.03217Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.03217Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.03217Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    142921,47587,56399
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0Direct
    50129,51735,50129
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 0Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.03217Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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