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Mammalian Phenotype (MP): abnormal embryo development

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   mammalian phenotype [MP:0000001] <29>
+ 1:   embryo phenotype [MP:0005380] <7>(40|54) (46|28|19)
0:   abnormal embryo development [MP:0001672] <5>(9|15) (11|11|5)
- 1:   abnormal developmental patterning [MP:0002084] <7>(7|12) (9|9|3)
- 1:   abnormal preimplantation embryo development [MP:0009781] <5>(0|0) (0|0|0)
- 1:   embryonic growth arrest [MP:0001730] <1>(1|0) (1|0|0)
- 1:   abnormal pharyngeal arch development [MP:0010395](0|0) (0|0|0)
- 1:   embryonic growth retardation [MP:0003984](1|1) (1|1|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
Notch domain0.000408Direct
DNA clamp0.00748Inherited
SMAD MH1 domain0.08709Inherited
SMAD/FHA domain0.2261Inherited
Cullin repeat-like0.2525Inherited
TIMP-like0.3637Inherited
WW domain0.3818Inherited
Frizzled cysteine-rich domain0.4199Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
DNA ligase0Direct
p53 tetramerization domain0Direct
DIX domain0.00003382Direct
Notch domain0.000228Direct
Cullin repeat0.001424Inherited
C5 cytosine-specific DNA methylase, DCM0.001424Inherited
SCF ubiquitin ligase complex WHB domain0.004848Inherited
SMAD MH1 domain0.05968Inherited
SMAD domain0.05968Inherited
Linker histone H1/H50.2037Inherited
Extracellular domain of cell surface receptors0.225Inherited
WW domain0.3408Inherited
Frizzled cysteine-rich domain0.351Inherited
Homeodomain1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
Notch domain0.0002136Direct
DNA clamp0.004583Inherited
SMAD MH1 domain0.06483Inherited
SMAD/FHA domain0.1875Inherited
Cullin homology domain0.212Inherited
Cullin repeat-like0.212Inherited
FnI-like domain0.3129Inherited
TIMP-like0.318Inherited
WW domain0.3357Inherited
Frizzled cysteine-rich domain0.373Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.0001581Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.001342Inherited
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.004583Inherited
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.004583Inherited
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.01016Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.212Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.2897Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.001342Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.2897Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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