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Mammalian Phenotype (MP): abnormal fluid regulation

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   homeostasis/metabolism phenotype [MP:0005376] <7>(140|174) (149|96|44)
+ 1:   abnormal homeostasis [MP:0001764] <27>(103|129) (113|73|31)
0:   abnormal fluid regulation [MP:0001784] <13>(9|17) (10|9|4)
- 1:   edema [MP:0001785] <17>(3|8) (3|3|0)
- 1:   ascites [MP:0005324] <2>(0|0) (0|0|0)
- 1:   decreased salivation [MP:0000623] <1>(0|0) (0|0|0)
- 1:   pericardial effusion [MP:0005312] <1>(1|1) (1|1|2)
- 1:   pleural effusion [MP:0010334] <1>(0|0) (0|0|0)
- 1:   abnormal amniotic fluid composition [MP:0012172](0|0) (0|0|0)
- 1:   abnormal renal water reabsorbtion [MP:0010108](0|0) (0|0|0)
- 1:   dehydration [MP:0001429](1|1) (1|0|0)
- 1:   hydropic allantois [MP:0012299](0|0) (0|0|0)
- 1:   impaired skin barrier function [MP:0002796](2|3) (2|1|0)
- 1:   increased salivation [MP:0000622](0|0) (0|0|0)
- 1:   oligohydramnios [MP:0012171](0|0) (0|0|0)
- 1:   polyhydramnios [MP:0004020](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
p53-like transcription factors0.00004747Direct
Inhibitor of apoptosis (IAP) repeat0.001587Inherited
HMG-box0.004736Inherited
Notch domain0.0394Inherited
Lipoxigenase0.07425Inherited
Intermediate filament protein, coiled coil region0.4241Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
p53 tetramerization domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Inhibitor of apoptosis (IAP) repeat0.0004548Direct
E2F dimerization segment0.0004548Direct
Platelet-derived growth factor-like0.0008502Direct
Pointed domain0.001196Inherited
T-box0.00258Inherited
HMG-box0.004443Inherited
Notch domain0.03125Inherited
Lipoxigenase N-terminal domain0.03125Inherited
Enabled/VASP homology 1 domain (EVH1 domain)0.03699Inherited
Animal lipoxigenases0.06187Inherited
Cyclin0.189Inherited
Intermediate filament protein, coiled coil region0.4249Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
p53 tetramerization domain0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
p53-like transcription factors0.00002228Direct
Inhibitor of apoptosis (IAP) repeat0.0008915Direct
E2F-DP heterodimerization region0.0008915Direct
HMG-box0.002824Inherited
Notch domain0.02728Inherited
Lipoxigenase0.05455Inherited
Intermediate filament protein, coiled coil region0.3774Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.000239Direct
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.0003353Direct
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.0006998Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.0008915Direct
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.002168Inherited
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.009079Inherited
    49723,48484
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 48484 - Lipoxigenase
  • 0.05455Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.1107Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.0003353Direct
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0008915Direct
    57924,57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.002168Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.03809Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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