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Mammalian Phenotype (MP): decreased IgG level

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + + + 9:   mammalian phenotype [MP:0000001] <29>
+ + + + + + + + 8:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + + + + 7:   abnormal hematopoietic system physiology [MP:0001545] <5>(39|53) (40|38|21)
+ + + + + + 6:   abnormal blood cell physiology [MP:0012382] <3>(38|53) (39|38|21)
+ + + + + 5:   abnormal immune cell physiology [MP:0001819] <3>(35|48) (37|33|21)
+ + + + + 5:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + + 5:   abnormal leukocyte physiology [MP:0002442] <5>(34|48) (36|33|20)
+ + + + + 5:   abnormal cell-mediated immunity [MP:0002421] <3>(35|48) (37|33|21)
+ + + + + 5:   abnormal adaptive immunity [MP:0002420] <8>(36|48) (38|33|21)
+ + + + 4:   abnormal professional antigen presenting cell physiology [MP:0002452] <3>(25|32) (26|19|12)
+ + + + 4:   abnormal immune system physiology [MP:0001790] <16>(59|84) (66|49|28)
+ + + + 4:   abnormal lymphocyte physiology [MP:0003945] <4>(21|31) (23|22|13)
+ + + 3:   abnormal immune serum protein physiology [MP:0002723] <4>(25|40) (31|24|12)
+ + + 3:   abnormal B cell physiology [MP:0002459] <9>(19|27) (20|16|10)
+ + + 3:   abnormal humoral immune response [MP:0001800] <4>(10|14) (12|10|8)
+ + 2:   abnormal immunoglobulin level [MP:0002490] <7>(8|12) (9|9|7)
+ 1:   abnormal IgG level [MP:0020174] <5>(6|11) (7|7|6)
+ 1:   decreased immunoglobulin level [MP:0002460] <5>(2|5) (2|4|2)
0:   decreased IgG level [MP:0001805] <3>(0|4) (0|3|2)
- 1:   decreased IgG2 level [MP:0013804] <3>(0|3) (0|3|1)
- 1:   decreased IgG1 level [MP:0008495](0|0) (0|2|2)
- 1:   decreased IgG3 level [MP:0008498](0|0) (0|2|1)


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Interleukin 17F, IL-17F0.00009074Direct
Rel/Dorsal transcription factors, DNA-binding domain0.05931Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.1623Inherited
V set domains (antibody variable domain-like)0.1686Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.061Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.205Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.00007564Direct