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Mammalian Phenotype (MP): abnormal T cell activation

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   mammalian phenotype [MP:0000001] <29>
+ + + + + + 6:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + + + 6:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + + 5:   abnormal immune system physiology [MP:0001790] <16>(59|84) (66|49|28)
+ + + + + 5:   abnormal hematopoietic system physiology [MP:0001545] <5>(39|53) (40|38|21)
+ + + + 4:   abnormal immune cell physiology [MP:0001819] <3>(35|48) (37|33|21)
+ + + + 4:   abnormal cell-mediated immunity [MP:0002421] <3>(35|48) (37|33|21)
+ + + + 4:   abnormal blood cell physiology [MP:0012382] <3>(38|53) (39|38|21)
+ + + + 4:   abnormal adaptive immunity [MP:0002420] <8>(36|48) (38|33|21)
+ + + 3:   abnormal leukocyte physiology [MP:0002442] <5>(34|48) (36|33|20)
+ + 2:   abnormal lymphocyte physiology [MP:0003945] <4>(21|31) (23|22|13)
+ 1:   abnormal T cell physiology [MP:0002444] <7>(8|15) (11|16|7)
0:   abnormal T cell activation [MP:0001828] <2>(3|7) (5|14|7)
- 1:   abnormal T cell proliferation [MP:0005094] <2>(1|4) (3|10|5)
- 1:   abnormal thymocyte activation [MP:0003850](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
STAT0.00000002782Direct
Transcription factor STAT-4 N-domain0.00000002782Direct
TNF receptor-like0.1587Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
STAT DNA-binding domain0.00000001614Direct
STAT0.00000001614Direct
Transcription factor STAT-4 N-domain0.00000001614Direct
V set domains (antibody variable domain-like)0.1125Inherited
TNF receptor-like0.1762Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.2428Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.3142Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
STAT0.00000001063Direct
Transcription factor STAT-4 N-domain0.00000001063Direct
DBL homology domain (DH-domain)0.02823Inherited
TNF receptor-like0.1263Inherited
Transducin (alpha subunit), insertion domain0.2111Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.00000001063Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.00000001063Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.00000001063Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.00001216Direct
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.00005652Direct
    49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 0.00006525Direct
    53300,69318
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 0.0001342Direct
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.003277Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.06427Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.1426Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2111Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.233Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.3111Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50044,55550,50044
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0Direct
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.00000001063Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.00000001063Direct
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.00006525Direct
    53300,69318,69179
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.0001342Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.001291Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)