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Mammalian Phenotype (MP): abnormal antigen presentation

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ 1:   abnormal immune system physiology [MP:0001790] <16>(59|84) (66|49|28)
0:   abnormal antigen presentation [MP:0001835] <6>(7|8) (7|4|2)
- 1:   abnormal antigen presentation via MHC class I [MP:0001836] <3>(1|1) (1|0|0)
- 1:   abnormal antigen presentation via MHC class II [MP:0005041] <2>(5|4) (5|3|2)
- 1:   abnormal B lymphocyte antigen presentation [MP:0002453] <1>(7|7) (7|4|2)
- 1:   abnormal dendritic cell antigen presentation [MP:0002455] <1>(1|1) (1|0|0)
- 1:   abnormal macrophage antigen presentation [MP:0002454] <1>(0|0) (0|0|0)
- 1:   abnormal follicular dendritic cell antigen presentation [MP:0008198](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
MHC antigen-recognition domain0.0001919Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0002003Direct
4-helical cytokines0.0005175Direct
STAT0.0009388Direct
Transcription factor STAT-4 N-domain0.0009388Direct
p53-like transcription factors0.01336Inherited
SH2 domain0.07195Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
C1 set domains (antibody constant domain-like)0.0000008314Direct
Proteasome subunits0.00003278Direct
MHC antigen-recognition domain0.0001337Direct
Short-chain cytokines0.0004925Direct
STAT DNA-binding domain0.0006376Direct
STAT0.0006376Direct
Transcription factor STAT-4 N-domain0.0006376Direct
SH2 domain0.06425Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
MHC antigen-recognition domain0.0000966Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0001013Direct
4-helical cytokines0.000274Direct
STAT0.0005099Direct
Transcription factor STAT-4 N-domain0.0005099Direct
p53-like transcription factors0.008512Inherited
SH2 domain0.05276Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.00002336Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0005099Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.0005099Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0005099Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0005099Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0005099Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)