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Mammalian Phenotype (MP): intestinal inflammation

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + 3:   digestive/alimentary phenotype [MP:0005381] <2>(38|46) (40|19|9)
+ + + 3:   abnormal immune system physiology [MP:0001790] <16>(59|84) (66|49|28)
+ + 2:   abnormal digestive system physiology [MP:0001663] <18>(16|16) (17|7|5)
+ + 2:   abnormal inflammatory response [MP:0001845] <4>(27|38) (29|18|5)
+ 1:   abnormal intestine physiology [MP:0010155] <4>(9|10) (9|6|4)
+ 1:   increased inflammatory response [MP:0001846] <35>(23|35) (25|17|4)
0:   intestinal inflammation [MP:0001858] <2>(8|9) (8|3|2)
- 1:   large intestinal inflammation [MP:0003304] <3>(8|9) (8|3|2)
- 1:   small intestinal inflammation [MP:0003306] <1>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
N-acetylmuramoyl-L-alanine amidase-like0Direct
DEATH domain0.003842Inherited
4-helical cytokines0.00512Inherited
Toll/Interleukin receptor TIR domain0.005927Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.01319Inherited
Riboflavin synthase domain-like0.01319Inherited
RNI-like0.01696Inherited
Nuclear receptor ligand-binding domain0.117Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
N-acetylmuramoyl-L-alanine amidase-like0Direct
Interleukin 17F, IL-17F0.0000005384Direct
Pyrin domain, PYD0.003032Inherited
Interferons/interleukin-10 (IL-10)0.003032Inherited
Caspase recruitment domain, CARD0.01052Inherited
28-residue LRR0.01073Inherited
Toll/Interleukin receptor TIR domain0.01299Inherited
Nuclear receptor ligand-binding domain0.1129Inherited
Nuclear receptor0.1129Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
N-acetylmuramoyl-L-alanine amidase-like0Direct
DEATH domain0.002259Inherited
4-helical cytokines0.003069Inherited
Toll/Interleukin receptor TIR domain0.003575Inherited
Riboflavin synthase domain-like0.008393Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.008393Inherited
RNI-like0.011Inherited
Nuclear receptor ligand-binding domain0.09011Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00001078Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.02546Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.05108Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.008393Inherited
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.008393Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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