SUPERFAMILY 1.75 HMM library and genome assignments server

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Mammalian Phenotype (MP): male infertility

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   reproductive system phenotype [MP:0005389] <2>(38|58) (47|18|6)
+ + 2:   abnormal reproductive system physiology [MP:0001919] <10>(21|39) (27|11|2)
+ + 2:   abnormal fertility/fecundity [MP:0002161] <7>(8|20) (10|3|0)
+ 1:   infertility [MP:0001924] <2>(2|7) (2|2|0)
+ 1:   abnormal male reproductive system physiology [MP:0003698] <12>(4|8) (4|4|0)
0:   male infertility [MP:0001925](2|5) (2|2|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
The spindle assembly checkpoint protein mad20.0004463Direct
E2F-DP heterodimerization region0.0005309Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Tudor domain0.00001196Direct
E2F dimerization segment0.0001016Direct
The spindle assembly checkpoint protein mad20.0002391Direct
DNA gyrase/MutL, second domain0.0002391Direct
DNA gyrase/MutL, N-terminal domain0.0002391Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
The spindle assembly checkpoint protein mad20.0002347Direct
E2F-DP heterodimerization region0.0002813Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.0002813Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0008672Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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