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Mammalian Phenotype (MP): increased leukemia incidence

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   mammalian phenotype [MP:0000001] <29>
+ + + + + 5:   neoplasm [MP:0002006] <2>(32|37) (38|18|7)
+ + + + 4:   altered tumor susceptibility [MP:0002166] <3>(25|29) (30|11|3)
+ + + 3:   abnormal tumor incidence [MP:0002019] <6>(25|29) (30|11|3)
+ + + 3:   abnormal organ/body region tumor incidence [MP:0013152] <2>(21|24) (24|8|3)
+ + 2:   increased tumor incidence [MP:0002020] <3>(25|27) (30|10|3)
+ + 2:   increased organ/body region tumor incidence [MP:0010274] <14>(21|24) (24|8|3)
+ + 2:   abnormal classified tumor incidence [MP:0020188] <3>(20|19) (26|7|1)
+ 1:   increased hemolymphoid system tumor incidence [MP:0010296] <7>(10|10) (10|4|1)
+ 1:   increased classified tumor incidence [MP:0010273] <19>(20|19) (26|7|1)
0:   increased leukemia incidence [MP:0002026] <4>(3|4) (3|3|1)
- 1:   increased acute lymphoblastic leukemia incidence [MP:0010336] <2>(0|0) (0|0|0)
- 1:   increased acute promyelocytic leukemia incidence [MP:0004049](0|0) (0|0|0)
- 1:   increased chronic lymphocytic leukemia incidence [MP:0010337](0|0) (0|0|0)
- 1:   increased chronic myelocytic leukemia incidence [MP:0005481](2|3) (2|2|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
Notch domain0.000003118Direct
p53-like transcription factors0.01366Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
p53 tetramerization domain0Direct
Notch domain0.000001952Direct
Phosphotyrosine-binding domain (PTB)0.005795Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
Notch domain0.000001319Direct
p53-like transcription factors0.008727Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.000000287Direct
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.004222Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0001146Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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