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Mammalian Phenotype (MP): abnormal ear morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   mammalian phenotype [MP:0000001] <29>
+ 1:   hearing/vestibular/ear phenotype [MP:0005377] <2>(20|24) (23|14|5)
0:   abnormal ear morphology [MP:0002102] <4>(16|21) (18|14|5)
- 1:   abnormal outer ear morphology [MP:0002177] <19>(0|1) (1|1|0)
- 1:   abnormal inner ear morphology [MP:0000026] <15>(13|15) (13|11|5)
- 1:   abnormal ear development [MP:0003938] <6>(1|0) (2|3|0)
- 1:   abnormal middle ear morphology [MP:0000049] <6>(3|5) (3|1|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Homeodomain-like0.0001304Direct
Serine protease inhibitors0.0003686Direct
Frizzled cysteine-rich domain0.0005087Direct
Cytokine0.01515Inherited
Cystine-knot cytokines0.02037Inherited
Cadherin-like0.02089Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.09985Inherited
Nicotinic receptor ligand binding domain-like0.09985Inherited
EGF/Laminin0.1332Inherited
Growth factor receptor domain0.1421Inherited
Nuclear receptor ligand-binding domain0.1845Inherited
PDZ domain-like0.1994Inherited
lambda repressor-like DNA-binding domains0.2405Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.279Inherited
Second domain of FERM0.4682Inherited
SH3-domain0.5447Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
Paired domain0.00002342Direct
Homeodomain0.00005957Direct
Frizzled cysteine-rich domain0.0003147Direct
Fibroblast growth factors (FGF)0.004421Inherited
DEP domain0.009476Inherited
Cadherin0.01224Inherited
Transforming growth factor (TGF)-beta0.01224Inherited
Transducin (alpha subunit), insertion domain0.02457Inherited
PDZ domain0.04341Inherited
Forkhead DNA-binding domain0.05506Inherited
Nicotinic receptor ligand binding domain-like0.0768Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.0768Inherited
Growth factor receptor domain0.1208Inherited
Nuclear receptor ligand-binding domain0.1506Inherited
Nuclear receptor0.1506Inherited
POU-specific domain0.204Inherited
DIX domain0.2806Inherited
EGF-type module0.359Inherited
SH3-domain0.5009Inherited
Motor proteins0.7273Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Homeodomain-like0.00006456Direct
Serine protease inhibitors0.0001919Direct
Frizzled cysteine-rich domain0.0002694Direct
Cytokine0.009729Inherited
Cystine-knot cytokines0.01338Inherited
Cadherin-like0.01375Inherited
Transducin (alpha subunit), insertion domain0.02262Inherited
Nicotinic receptor ligand binding domain-like0.07534Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.07534Inherited
EGF/Laminin0.1039Inherited
Growth factor receptor domain0.1117Inherited
Nuclear receptor ligand-binding domain0.1493Inherited
PDZ domain-like0.1628Inherited
lambda repressor-like DNA-binding domains0.2009Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.237Inherited
GTPase activation domain, GAP0.2929Inherited
Second domain of FERM0.4203Inherited
SH3-domain0.4979Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.001601Inherited
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.003056Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0095Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.01779Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01837Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.04485Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.06847Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.07534Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1178Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.1453Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.2009Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.2773Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.332Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.5187Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.007228Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1556Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.2009Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.5256Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.5256Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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