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Mammalian Phenotype (MP): abnormal limb morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   mammalian phenotype [MP:0000001] <29>
+ 1:   limbs/digits/tail phenotype [MP:0005371] <2>(18|26) (22|21|17)
0:   abnormal limb morphology [MP:0002109] <13>(12|21) (15|17|16)
- 1:   abnormal autopod morphology [MP:0000572] <11>(6|12) (7|7|8)
- 1:   abnormal limb development [MP:0006279] <6>(2|3) (3|0|0)
- 1:   limb wound [MP:0013069] <6>(0|0) (0|0|0)
- 1:   abnormal limb bone morphology [MP:0002115] <5>(5|9) (7|8|8)
- 1:   abnormal hindlimb morphology [MP:0000556] <4>(3|6) (5|5|3)
- 1:   abnormal forelimb morphology [MP:0000550] <3>(2|7) (3|2|0)
- 1:   absent limbs [MP:0000549] <2>(1|1) (1|0|0)
- 1:   short limbs [MP:0000547] <1>(0|0) (0|0|0)
- 1:   abnormal limb position [MP:0012000](0|0) (0|0|0)
- 1:   ectopic limbs [MP:0020288](0|0) (0|0|0)
- 1:   hemimelia [MP:0008985](0|0) (0|0|0)
- 1:   long limbs [MP:0000548](0|0) (0|0|0)
- 1:   pale limbs [MP:0013133](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Kringle-like0.004173Inherited
Cystine-knot cytokines0.005634Inherited
Cytokine0.01333Inherited
Metalloproteases ("zincins"), catalytic domain0.01426Inherited
CalX-like0.02138Inherited
PGBD-like0.06933Inherited
Integrin domains0.167Inherited
TIMP-like0.2633Inherited
Intermediate filament protein, coiled coil region0.3564Inherited
YWTD domain0.4824Inherited
TSP type-3 repeat0.5604Inherited
Homeodomain-like0.8222Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
Transforming growth factor (TGF)-beta0.002078Inherited
Fibroblast growth factors (FGF)0.00297Inherited
Ovomucoid domain III-like0.004035Inherited
Proprotein convertase P-domain0.005346Inherited
Prohormone convertase 1 pro-domain0.005346Inherited
CalX-beta domain0.0158Inherited
Kringle modules0.02368Inherited
Hemopexin-like domain0.03155Inherited
MMP N-terminal domain0.05607Inherited
Matrix metalloproteases, catalytic domain0.06648Inherited
Reprolysin-like0.1115Inherited
Integrin domains0.1447Inherited
HMG-box0.1691Inherited
Intermediate filament protein, coiled coil region0.3246Inherited
YWTD domain0.4492Inherited
Thrombospondin C-terminal domain0.5279Inherited
TSP type-3 repeat0.5279Inherited
VWC domain0.6077Inherited
T-box0.6077Inherited
Homeodomain0.7954Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Kringle-like0.002468Inherited
Cystine-knot cytokines0.003395Inherited
Cytokine0.008494Inherited
Metalloproteases ("zincins"), catalytic domain0.009143Inherited
CalX-like0.0141Inherited
Hemopexin-like domain0.02807Inherited
PGBD-like0.05069Inherited
Integrin domains0.1335Inherited
HMG-box0.1587Inherited
TIMP-like0.222Inherited
Intermediate filament protein, coiled coil region0.3108Inherited
YWTD domain0.4347Inherited
TSP type-3 repeat0.5138Inherited
Homeodomain-like0.7889Inherited
LDL receptor-like module0.84Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.0003147Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.0004091Direct
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.000841Direct
    48726,56436
  • 48726 - Immunoglobulin
  • 56436 - C-type lectin-like
  • 0.004708Inherited
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.004708Inherited
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0.0141Inherited
    55486,82895
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 82895 - TSP-1 type 1 repeat
  • 0.01589Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.05069Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.107Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.3674Inherited
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.4347Inherited
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.4347Inherited
    103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0.5138Inherited
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.5138Inherited
    103647,49899
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.5138Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.6577Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.0003147Direct
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.0003147Direct
    57196,57581,57184
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0.0005798Direct
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.000841Direct
    48726,56436,56436
  • 48726 - Immunoglobulin
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.004708Inherited
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.004708Inherited
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.004708Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.008063Inherited
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.09126Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.1358Inherited
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.4347Inherited
    103647,103647,49899
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.5138Inherited
    103647,103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0.5138Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.6577Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)