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Mammalian Phenotype (MP): abnormal craniofacial bone morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   skeleton phenotype [MP:0005390] <2>(46|63) (50|41|26)
+ + 2:   abnormal skeleton morphology [MP:0005508] <15>(41|59) (47|38|25)
+ + 2:   craniofacial phenotype [MP:0005382] <1>(20|36) (24|17|10)
+ 1:   abnormal axial skeleton morphology [MP:0002114] <4>(24|40) (25|21|14)
+ 1:   abnormal craniofacial morphology [MP:0000428] <5>(20|36) (24|17|10)
0:   abnormal craniofacial bone morphology [MP:0002116] <3>(16|25) (16|13|7)
- 1:   abnormal cranium morphology [MP:0000438] <11>(16|25) (16|13|7)
- 1:   abnormal middle ear ossicle morphology [MP:0005105] <7>(2|3) (2|1|0)
- 1:   absent craniofacial bones [MP:0000073](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
TB module/8-cys domain0.001885Inherited
Growth factor receptor domain0.0101Inherited
PGBD-like0.01377Inherited
Cystine-knot cytokines0.01975Inherited
Hemopexin-like domain0.02585Inherited
Metalloproteases ("zincins"), catalytic domain0.03289Inherited
EGF/Laminin0.05317Inherited
p53-like transcription factors0.06738Inherited
lambda repressor-like DNA-binding domains0.1107Inherited
Homeodomain-like0.1204Inherited
FnI-like domain0.1529Inherited
4-helical cytokines0.1769Inherited
Transducin (alpha subunit), insertion domain0.3907Inherited
Nuclear receptor ligand-binding domain0.4752Inherited
Bromodomain0.8325Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
p53 tetramerization domain0Direct
Paired domain0.0000003579Direct
Arylsulfatase0.0002279Direct
Rel/Dorsal transcription factors, DNA-binding domain0.0004663Direct
TB module/8-cys domain0.001353Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.00328Inherited
Neutral endopeptidase (neprilysin)0.007172Inherited
Laminin-type module0.007758Inherited
Growth factor receptor domain0.01005Inherited
MMP N-terminal domain0.01108Inherited
Transforming growth factor (TGF)-beta0.01239Inherited
Matrix metalloproteases, catalytic domain0.01403Inherited
Hemopexin-like domain0.02141Inherited
Forkhead DNA-binding domain0.03222Inherited
TNF receptor-like0.08295Inherited
DEATH domain, DD0.08295Inherited
Homeodomain0.08862Inherited
G proteins0.3117Inherited
Extracellular domain of cell surface receptors0.3582Inherited
Transducin (alpha subunit), insertion domain0.3582Inherited
Nuclear receptor ligand-binding domain0.4449Inherited
Nuclear receptor0.4449Inherited
T-box0.5781Inherited
Bromodomain0.8129Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
TB module/8-cys domain0.001069Inherited
Growth factor receptor domain0.006311Inherited
PGBD-like0.008805Inherited
Cystine-knot cytokines0.01294Inherited
Hemopexin-like domain0.01732Inherited
Metalloproteases ("zincins"), catalytic domain0.0225Inherited
EGF/Laminin0.03773Inherited
p53-like transcription factors0.04907Inherited
lambda repressor-like DNA-binding domains0.08468Inherited
Homeodomain-like0.09287Inherited
FnI-like domain0.1213Inherited
4-helical cytokines0.1424Inherited
Transducin (alpha subunit), insertion domain0.3443Inherited
Nuclear receptor ligand-binding domain0.4276Inherited
Bromodomain0.8002Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.0001817Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.0003535Direct
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.0004995Direct
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.003185Inherited
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.003185Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.008805Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.04855Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.05243Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.09733Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.1662Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.1662Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2111Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,57581
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.00136Inherited
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00136Inherited
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.009731Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.01869Inherited
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.04823Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.07735Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.4569Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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