SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Mammalian Phenotype (MP): abnormal hepatobiliary system physiology

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   mammalian phenotype [MP:0000001] <29>
+ 1:   liver/biliary system phenotype [MP:0005370] <2>(37|39) (41|19|10)
0:   abnormal hepatobiliary system physiology [MP:0002139] <4>(16|14) (16|10|7)
- 1:   abnormal liver physiology [MP:0000609] <9>(13|11) (13|9|7)
- 1:   abnormal bile duct physiology [MP:0003252] <6>(0|0) (0|0|0)
- 1:   abnormal gallbladder physiology [MP:0005085] <4>(3|3) (3|1|0)
- 1:   abnormal hepatoblast physiology [MP:0012241] <2>(0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
STAT0.000005199Direct
Transcription factor STAT-4 N-domain0.000005199Direct
Alpha-macroglobulin receptor domain0.0001772Direct
C-type lectin-like0.000735Direct
p53-like transcription factors0.003951Inherited
TNF receptor-like0.008427Inherited
Leucine zipper domain0.01087Inherited
DEATH domain0.01523Inherited
SH2 domain0.02865Inherited
Kringle-like0.02895Inherited
Terpenoid cyclases/Protein prenyltransferases0.03674Inherited
4-helical cytokines0.04332Inherited
ABC transporter transmembrane region0.05412Inherited
Bet v1-like0.2777Inherited
lambda repressor-like DNA-binding domains0.2777Inherited
Family A G protein-coupled receptor-like0.6433Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Rel/Dorsal transcription factors, DNA-binding domain0.000003035Direct
STAT DNA-binding domain0.000003607Direct
STAT0.000003607Direct
Transcription factor STAT-4 N-domain0.000003607Direct
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.00005212Direct
Complement components0.0001248Direct
Alpha-macroglobulin receptor domain0.0001248Direct
Leucine zipper domain0.008937Inherited
TNF receptor-like0.01398Inherited
SH2 domain0.02582Inherited
DEATH domain, DD0.03036Inherited
ABC transporter ATPase domain-like0.03766Inherited
ABC transporter transmembrane region0.08412Inherited
Rhodopsin-like0.5805Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
STAT0.000002221Direct
Transcription factor STAT-4 N-domain0.000002221Direct
Alpha-macroglobulin receptor domain0.00008893Direct
C-type lectin-like0.0003943Direct
p53-like transcription factors0.002328Inherited
TNF receptor-like0.005202Inherited
Leucine zipper domain0.006835Inherited
DEATH domain0.009786Inherited
SH2 domain0.01937Inherited
Kringle-like0.0196Inherited
Terpenoid cyclases/Protein prenyltransferases0.02531Inherited
4-helical cytokines0.03023Inherited
ABC transporter transmembrane region0.03848Inherited
Bet v1-like0.2358Inherited
lambda repressor-like DNA-binding domains0.2358Inherited
Family A G protein-coupled receptor-like0.5994Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.000001767Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.000002221Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.000002221Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.000002221Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.00002346Direct
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.0003878Direct
    103473,100895
  • 103473 - MFS general substrate transporter
  • 100895 - Kazal-type serine protease inhibitors
  • 0.0008558Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.02531Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.03848Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.000002221Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.000002221Direct
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0003547Direct
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.0008558Direct
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.0008558Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)