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Mammalian Phenotype (MP): abnormal hepatobiliary system physiology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   mammalian phenotype [MP:0000001] <29>
+ 1:   liver/biliary system phenotype [MP:0005370] <2>(37|39) (41|19|10)
0:   abnormal hepatobiliary system physiology [MP:0002139] <4>(16|14) (16|10|7)
- 1:   abnormal liver physiology [MP:0000609] <9>(13|11) (13|9|7)
- 1:   abnormal bile duct physiology [MP:0003252] <6>(0|0) (0|0|0)
- 1:   abnormal gallbladder physiology [MP:0005085] <4>(3|3) (3|1|0)
- 1:   abnormal hepatoblast physiology [MP:0012241] <2>(0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
STAT0.000005183Direct
Transcription factor STAT-4 N-domain0.000005183Direct
Alpha-macroglobulin receptor domain0.000177Direct
C-type lectin-like0.0007349Direct
p53-like transcription factors0.003952Inherited
TNF receptor-like0.008428Inherited
Leucine zipper domain0.01087Inherited
DEATH domain0.01523Inherited
SH2 domain0.02865Inherited
Kringle-like0.02896Inherited
Terpenoid cyclases/Protein prenyltransferases0.03675Inherited
4-helical cytokines0.0433Inherited
ABC transporter transmembrane region0.05412Inherited
lambda repressor-like DNA-binding domains0.2778Inherited
Bet v1-like0.2778Inherited
Family A G protein-coupled receptor-like0.6431Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Rel/Dorsal transcription factors, DNA-binding domain0.000003032Direct
STAT DNA-binding domain0.000003604Direct
Transcription factor STAT-4 N-domain0.000003604Direct
STAT0.000003604Direct
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.00005206Direct
Complement components0.0001247Direct
Alpha-macroglobulin receptor domain0.0001247Direct
Leucine zipper domain0.008944Inherited
TNF receptor-like0.01399Inherited
SH2 domain0.02583Inherited
DEATH domain, DD0.03038Inherited
ABC transporter ATPase domain-like0.03767Inherited
ABC transporter transmembrane region0.08419Inherited
Rhodopsin-like0.5802Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
STAT0.000002218Direct
Transcription factor STAT-4 N-domain0.000002218Direct
Alpha-macroglobulin receptor domain0.0000889Direct
C-type lectin-like0.0003944Direct
p53-like transcription factors0.002329Inherited
TNF receptor-like0.005203Inherited
Leucine zipper domain0.006837Inherited
DEATH domain0.009786Inherited
SH2 domain0.01937Inherited
Kringle-like0.01961Inherited
Terpenoid cyclases/Protein prenyltransferases0.02532Inherited
4-helical cytokines0.03024Inherited
ABC transporter transmembrane region0.0385Inherited
Bet v1-like0.2358Inherited
lambda repressor-like DNA-binding domains0.2358Inherited
Family A G protein-coupled receptor-like0.5992Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.000001765Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.000002218Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.000002218Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.000002218Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.00002342Direct
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.0003877Direct
    103473,100895
  • 103473 - MFS general substrate transporter
  • 100895 - Kazal-type serine protease inhibitors
  • 0.0008556Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.02532Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0385Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.000002218Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.000002218Direct
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0003547Direct
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.0008556Direct
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.0008556Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)