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Mammalian Phenotype (MP): abnormal neural tube morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   embryo phenotype [MP:0005380] <7>(40|54) (46|28|19)
+ + + 3:   nervous system phenotype [MP:0003631] <2>(98|128) (113|79|50)
+ + 2:   abnormal embryo morphology [MP:0014134] <4>(23|31) (26|14|12)
+ + 2:   abnormal nervous system morphology [MP:0003632] <17>(76|104) (91|64|47)
+ 1:   abnormal embryonic tissue morphology [MP:0002085] <35>(17|21) (19|10|9)
+ 1:   abnormal nervous system development [MP:0003861] <9>(19|31) (21|14|10)
0:   abnormal neural tube morphology [MP:0002151] <16>(7|8) (7|4|3)
- 1:   abnormal embryonic neuroepithelium morphology [MP:0004261] <5>(1|2) (1|1|0)
- 1:   abnormal neural tube closure [MP:0003720] <4>(2|3) (3|2|1)
- 1:   abnormal floor plate morphology [MP:0000925] <3>(0|0) (0|0|1)
- 1:   abnormal neural tube mantle layer morphology [MP:0009690] <2>(0|0) (0|0|0)
- 1:   abnormal neuropore morphology [MP:0012542] <2>(0|0) (0|0|0)
- 1:   abnormal lamina terminalis morphology [MP:0012540] <1>(0|0) (0|0|0)
- 1:   abnormal neural crest morphology [MP:0009846] <1>(0|0) (0|0|0)
- 1:   abnormal neuromere morphology [MP:0003208] <1>(1|1) (1|0|0)
- 1:   abnormal roof plate morphology [MP:0000923] <1>(0|0) (0|0|0)
- 1:   abnormal neural tube marginal layer morphology [MP:0009691](0|0) (0|0|0)
- 1:   abnormal neural tube ventricular layer morphology [MP:0009689](0|0) (0|0|0)
- 1:   caudal rachischisis [MP:0009245](0|0) (0|0|0)
- 1:   craniorachischisis [MP:0008784](2|3) (2|1|0)
- 1:   kinked neural tube [MP:0003400](0|0) (0|0|0)
- 1:   neural tube degeneration [MP:0012509](0|0) (0|0|0)
- 1:   wavy neural tube [MP:0000930](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
HCP-like0.0005353Direct
Formate/glycerate dehydrogenase catalytic domain-like0.00352Inherited
Frizzled cysteine-rich domain0.005856Inherited
Homeodomain-like0.1203Inherited
Bromodomain0.1999Inherited
TIMP-like0.3139Inherited
PDZ domain-like0.5526Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
DIX domain0.000002418Direct
Formate/glycerate dehydrogenases, substrate-binding domain0.0002819Direct
Formate/glycerate dehydrogenases, NAD-domain0.002404Inherited
Frizzled cysteine-rich domain0.003593Inherited
DEP domain0.06575Inherited
Homeodomain0.1083Inherited
Bromodomain0.164Inherited
PDZ domain0.5724Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
HCP-like0.0002837Direct
Formate/glycerate dehydrogenase catalytic domain-like0.002062Inherited
Frizzled cysteine-rich domain0.003529Inherited
Homeodomain-like0.09277Inherited
Bromodomain0.1633Inherited
TIMP-like0.2699Inherited
PDZ domain-like0.5058Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.0002358Direct
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.0008715Direct
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.002062Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.1794Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0008715Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.08795Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.4072Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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