SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Mammalian Phenotype (MP): abnormal fertility/fecundity

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   reproductive system phenotype [MP:0005389] <2>(38|58) (47|18|6)
+ 1:   abnormal reproductive system physiology [MP:0001919] <10>(21|39) (27|11|2)
0:   abnormal fertility/fecundity [MP:0002161] <7>(8|20) (10|3|0)
- 1:   abnormal litter size [MP:0001933] <2>(2|9) (6|0|0)
- 1:   delayed fertility [MP:0002683] <2>(0|0) (0|0|0)
- 1:   infertility [MP:0001924] <2>(2|7) (2|2|0)
- 1:   reduced fertility [MP:0001921] <2>(2|6) (2|1|0)
- 1:   delayed reproductive senescence [MP:0013475](0|0) (0|0|0)
- 1:   early reproductive senescence [MP:0008995](2|2) (2|0|0)
- 1:   enhanced fertility [MP:0010143](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
SMAD MH1 domain0.00001325Direct
Tudor/PWWP/MBT0.0001029Direct
The spindle assembly checkpoint protein mad20.006321Inherited
E2F-DP heterodimerization region0.01235Inherited
Flavoproteins0.01235Inherited
Alkaline phosphatase-like0.1193Inherited
SMAD/FHA domain0.4073Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Tudor domain0.000003097Direct
SMAD MH1 domain0.00000776Direct
SMAD domain0.00000776Direct
Linker histone H1/H50.0006761Direct
Gonadodropin/Follitropin0.0009606Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.0009606Direct
NADPH-cytochrome p450 reductase-like0.0009606Direct
E2F dimerization segment0.00371Inherited
Neurotrophin0.004353Inherited
The spindle assembly checkpoint protein mad20.004353Inherited
gamma-adaptin C-terminal appendage domain-like0.004353Inherited
DNA gyrase/MutL, second domain0.004353Inherited
DNA gyrase/MutL, N-terminal domain0.004353Inherited
Astacin0.02846Inherited
Transforming growth factor (TGF)-beta0.2016Inherited
Nuclear receptor0.506Inherited
Nuclear receptor ligand-binding domain0.6647Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
SMAD MH1 domain0.000005861Direct
Tudor/PWWP/MBT0.00004987Direct
The spindle assembly checkpoint protein mad20.003842Inherited
E2F-DP heterodimerization region0.007841Inherited
Flavoproteins0.007841Inherited
Alkaline phosphatase-like0.092Inherited
SMAD/FHA domain0.3605Inherited
Nuclear receptor ligand-binding domain0.677Inherited
PYP-like sensor domain (PAS domain)0.7775Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.007841Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.01223Inherited
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0.06744Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)