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Mammalian Phenotype (MP): abnormal gland physiology

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   mammalian phenotype [MP:0000001] <29>
+ 1:   endocrine/exocrine gland phenotype [MP:0005379] <2>(51|81) (55|36|12)
0:   abnormal gland physiology [MP:0002164] <4>(9|19) (11|11|5)
- 1:   abnormal exocrine gland physiology [MP:0013559] <9>(4|7) (5|7|4)
- 1:   abnormal pancreas physiology [MP:0002693] <8>(5|12) (5|7|3)
- 1:   abnormal endocrine gland physiology [MP:0013561] <6>(4|10) (4|6|2)
- 1:   abnormal sex gland physiology [MP:0005647] <4>(1|2) (2|1|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Caspase-like0.001689Inherited
STAT0.009894Inherited
Transcription factor STAT-4 N-domain0.009894Inherited
p53-like transcription factors0.02284Inherited
Nuclear receptor ligand-binding domain0.02968Inherited
IP3 receptor type 1 binding core, domain 20.05133Inherited
MIR domain0.05133Inherited
Thyroglobulin type-1 domain0.1245Inherited
Growth factor receptor domain0.2457Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
IP3 receptor type 1 binding core, domain 20Direct
Caspase catalytic domain0.001244Inherited
STAT DNA-binding domain0.007548Inherited
STAT0.007548Inherited
Transcription factor STAT-4 N-domain0.007548Inherited
Forkhead DNA-binding domain0.01647Inherited
Nuclear receptor ligand-binding domain0.02703Inherited
Nuclear receptor0.02984Inherited
MIR domain0.04134Inherited
L domain0.05377Inherited
FYVE, a phosphatidylinositol-3-phosphate binding domain0.07156Inherited
Ras-binding domain, RBD0.09333Inherited
Thyroglobulin type-1 domain0.1075Inherited
Papain-like0.1075Inherited
Caspase recruitment domain, CARD0.1899Inherited
V set domains (antibody variable domain-like)0.2185Inherited
Growth factor receptor domain0.2315Inherited
EGF-type module0.2462Inherited
Pleckstrin-homology domain (PH domain)0.288Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Caspase-like0.0009522Direct
STAT0.006172Inherited
Transcription factor STAT-4 N-domain0.006172Inherited
p53-like transcription factors0.01514Inherited
Nuclear receptor ligand-binding domain0.02017Inherited
IP3 receptor type 1 binding core, domain 20.0363Inherited
MIR domain0.0363Inherited
Thyroglobulin type-1 domain0.09636Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.1091Inherited
Growth factor receptor domain0.2059Inherited
EGF/Laminin0.2451Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57184,57610
  • 57184 - Growth factor receptor domain
  • 57610 - Thyroglobulin type-1 domain
  • 0.003378Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.006172Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.006172Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.006172Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.01203Inherited
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.01511Inherited
    82109,100909
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.0363Inherited
    82109,82109
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 0.0363Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.04678Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.04678Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.5181Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.006172Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.006172Inherited
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.0363Inherited
    82109,82109,100909
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 0.0363Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.04678Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)