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Mammalian Phenotype (MP): abnormal germ cell morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   reproductive system phenotype [MP:0005389] <2>(38|58) (47|18|6)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   cellular phenotype [MP:0005384] <6>(95|116) (103|56|31)
+ + 2:   abnormal reproductive system morphology [MP:0002160] <12>(28|46) (37|15|6)
+ 1:   abnormal gametogenesis [MP:0001929] <7>(15|19) (19|3|1)
+ 1:   abnormal cell morphology [MP:0000358] <12>(19|19) (22|9|2)
0:   abnormal germ cell morphology [MP:0002208] <5>(11|12) (13|2|1)
- 1:   abnormal male germ cell morphology [MP:0006362] <5>(7|8) (9|2|0)
- 1:   abnormal gametes [MP:0001124] <4>(4|6) (7|1|0)
- 1:   decreased germ cell number [MP:0002209] <4>(8|11) (11|2|0)
- 1:   abnormal female germ cell morphology [MP:0006361] <3>(4|3) (4|0|0)
- 1:   abnormal primordial germ cell morphology [MP:0008391] <2>(2|2) (2|0|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
SMAD MH1 domain0.000002465Direct
PAZ domain0.00007844Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.005083Inherited
SMAD/FHA domain0.009679Inherited
Cystine-knot cytokines0.01106Inherited
Bcl-2 inhibitors of programmed cell death0.01616Inherited
Nuclear receptor ligand-binding domain0.05531Inherited
The spindle assembly checkpoint protein mad20.1735Inherited
Tudor/PWWP/MBT0.1891Inherited
Nucleic acid-binding proteins0.2184Inherited
BAR/IMD domain-like0.2893Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
SMAD MH1 domain0.000001094Direct
SMAD domain0.000001094Direct
PAZ domain0.00003799Direct
DNA gyrase/MutL, second domain0.000257Direct
DNA gyrase/MutL, N-terminal domain0.000257Direct
Transforming growth factor (TGF)-beta0.001128Inherited
Insulin-like0.001245Inherited
Bcl-2 inhibitors of programmed cell death0.01056Inherited
Nuclear receptor ligand-binding domain0.03957Inherited
Single strand DNA-binding domain, SSB0.08567Inherited
The spindle assembly checkpoint protein mad20.1409Inherited
Tudor domain0.287Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SMAD MH1 domain0.000001028Direct
PAZ domain0.00003752Direct
Insulin-like0.001242Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.003045Inherited
SMAD/FHA domain0.006031Inherited
Cystine-knot cytokines0.006959Inherited
Bcl-2 inhibitors of programmed cell death0.01044Inherited
Nuclear receptor ligand-binding domain0.03943Inherited
The spindle assembly checkpoint protein mad20.1392Inherited
Tudor/PWWP/MBT0.1535Inherited
Nucleic acid-binding proteins0.1803Inherited
dsRNA-binding domain-like0.2078Inherited
BAR/IMD domain-like0.2466Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0009292Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.1392Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.1342Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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