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Mammalian Phenotype (MP): decreased germ cell number

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   reproductive system phenotype [MP:0005389] <2>(38|58) (47|18|6)
+ + + 3:   abnormal reproductive system morphology [MP:0002160] <12>(28|46) (37|15|6)
+ + + 3:   cellular phenotype [MP:0005384] <6>(95|116) (103|56|31)
+ + 2:   abnormal cell morphology [MP:0000358] <12>(19|19) (22|9|2)
+ + 2:   abnormal gametogenesis [MP:0001929] <7>(15|19) (19|3|1)
+ 1:   abnormal germ cell morphology [MP:0002208] <5>(11|12) (13|2|1)
0:   decreased germ cell number [MP:0002209] <4>(8|11) (11|2|0)
- 1:   absent germ cells [MP:0004806] <2>(4|6) (6|0|0)
- 1:   decreased male germ cell number [MP:0004901] <2>(5|6) (7|2|0)
- 1:   decreased oocyte number [MP:0005431] <1>(0|1) (1|0|0)
- 1:   decreased primordial germ cell number [MP:0008392] <1>(2|2) (2|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
PAZ domain0.00001841Direct
The spindle assembly checkpoint protein mad20.000189Direct
Nucleic acid-binding proteins0.0002883Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.001522Inherited
Bcl-2 inhibitors of programmed cell death0.007355Inherited
Nuclear receptor ligand-binding domain0.1675Inherited
SMAD/FHA domain0.2007Inherited
SMAD MH1 domain0.3455Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
PAZ domain0.000008771Direct
Single strand DNA-binding domain, SSB0.00009648Direct
The spindle assembly checkpoint protein mad20.00009923Direct
DNA gyrase/MutL, second domain0.00009923Direct
DNA gyrase/MutL, N-terminal domain0.00009923Direct
Bcl-2 inhibitors of programmed cell death0.004646Inherited
Nuclear receptor ligand-binding domain0.1426Inherited
SMAD MH1 domain0.3132Inherited
SMAD domain0.3132Inherited
Tudor domain0.3132Inherited
Transforming growth factor (TGF)-beta0.5432Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
PAZ domain0.00000819Direct
The spindle assembly checkpoint protein mad20.00009508Direct
Nucleic acid-binding proteins0.0001479Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.0008535Direct
Bcl-2 inhibitors of programmed cell death0.004518Inherited
dsRNA-binding domain-like0.007315Inherited
Tudor/PWWP/MBT0.1093Inherited
Nuclear receptor ligand-binding domain0.1339Inherited
SMAD/FHA domain0.1639Inherited
SMAD MH1 domain0.3002Inherited
Cystine-knot cytokines0.4183Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.0003675Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0003675Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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