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Mammalian Phenotype (MP): abnormal sex determination

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   reproductive system phenotype [MP:0005389] <2>(38|58) (47|18|6)
+ 1:   abnormal reproductive system morphology [MP:0002160] <12>(28|46) (37|15|6)
0:   abnormal sex determination [MP:0002210] <3>(7|18) (12|6|3)
- 1:   abnormal primary sex determination [MP:0002211] <6>(6|12) (10|6|3)
- 1:   abnormal secondary sex determination [MP:0002212] <3>(0|2) (0|0|0)
- 1:   sex reversal [MP:0005652] <2>(1|3) (2|4|3)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
PAZ domain0.00006221Direct
The spindle assembly checkpoint protein mad20.0004121Direct
Nucleic acid-binding proteins0.001466Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.0291Inherited
Protein kinase-like (PK-like)0.213Inherited
Homeodomain-like0.2757Inherited
Tudor/PWWP/MBT0.3092Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
PAS domain of steroid receptor coactivator 1A, NCo-A10Direct
PAZ domain0.00003976Direct
The spindle assembly checkpoint protein mad20.0002652Direct
DNA gyrase/MutL, second domain0.0002652Direct
DNA gyrase/MutL, N-terminal domain0.0002652Direct
Single strand DNA-binding domain, SSB0.0003206Direct
Gonadodropin/Follitropin0.0009684Direct
Nuclear receptor coactivator interlocking domain0.0009684Direct
Insulin-like0.07187Inherited
Tudor domain0.1017Inherited
L domain0.123Inherited
Protein kinases, catalytic subunit0.1762Inherited
Homeodomain0.2254Inherited
Extracellular domain of cell surface receptors0.4295Inherited
Nuclear receptor ligand-binding domain0.4562Inherited
Nuclear receptor0.616Inherited
Growth factor receptor domain0.757Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
PAZ domain0.00002938Direct
The spindle assembly checkpoint protein mad20.0002159Direct
Nuclear receptor coactivator interlocking domain0.0008017Direct
Nucleic acid-binding proteins0.0008209Direct
Ribonuclease H-like0.002222Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.01971Inherited
Insulin-like0.06303Inherited
Protein kinase-like (PK-like)0.1753Inherited
Homeodomain-like0.2339Inherited
Tudor/PWWP/MBT0.2654Inherited
Nuclear receptor ligand-binding domain0.4077Inherited
Growth factor receptor domain0.8615Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52058,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.0008017Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0008017Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.1107Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.1107Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.5126Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,52058,49265
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0Direct
    52058,49265,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.1107Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)