SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Mammalian Phenotype (MP): abnormal pulmonary alveolus morphology

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   mammalian phenotype [MP:0000001] <29>
+ + + + + 5:   respiratory system phenotype [MP:0005388] <2>(33|46) (36|29|15)
+ + + + 4:   abnormal respiratory system morphology [MP:0002132] <12>(22|34) (27|22|13)
+ + + 3:   abnormal lung morphology [MP:0001175] <18>(15|25) (17|18|12)
+ + 2:   abnormal pulmonary alveolar system morphology [MP:0010899] <2>(3|7) (3|10|5)
+ 1:   abnormal pulmonary acinus morphology [MP:0010911] <6>(3|6) (3|8|4)
0:   abnormal pulmonary alveolus morphology [MP:0002270] <6>(3|5) (3|6|4)
- 1:   abnormal pulmonary alveolus epithelium morphology [MP:0010898] <1>(1|1) (1|1|0)
- 1:   abnormal pulmonary alveolus wall morphology [MP:0010903](0|0) (0|0|0)
- 1:   absent pulmonary alveoli [MP:0001184](0|0) (0|0|0)
- 1:   calcified pulmonary alveolus [MP:0010923](0|0) (0|0|0)
- 1:   overexpanded pulmonary alveoli [MP:0001183](2|3) (2|2|2)
- 1:   pulmonary alveolar proteinosis [MP:0010998](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
FnI-like domain0.004163Inherited
PGBD-like0.00879Inherited
Hemopexin-like domain0.01377Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Hypoxia-inducible factor Hif2a, C-terminal domain0.0002759Direct
MMP N-terminal domain0.007041Inherited
Matrix metalloproteases, catalytic domain0.008354Inherited
Hemopexin-like domain0.01127Inherited
Phosphotyrosine-binding domain (PTB)0.01561Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
FnI-like domain0.002462Inherited
PGBD-like0.005434Inherited
Hemopexin-like domain0.008805Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0002526Direct
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.0004641Direct
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.0004801Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.004514Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.005434Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.01151Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.00007819Direct
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0001614Direct
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.0002877Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0009986Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)